Recombinant multi-species COX7A2L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX7A2L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016]
The Alternative Names of target: COX7A2L,COX7AR,COX7RP,Cox7a2l,Cytochrome c oxidase subunit 7A-related protein (COX7a-related protein),Cytochrome c oxidase subunit 7A2-like,Cytochrome c oxidase subunit VIIa-related protein,EB1,SCAF1,SCAFI,SIG-81,SIG81,Scaf1,Silg81,Supercomplex assembly factor 1,mitochondrial

Target products collectionGo to COX7A2L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13550-Ag-1/ GM-Tg-hg-IP13550-Ag-2 Human COX7A2L protein Human
GM-Tg-rg-IP13550-Ag-1/ GM-Tg-rg-IP13550-Ag-2 Rat COX7A2L protein Rat
GM-Tg-mg-IP13550-Ag-1/ GM-Tg-mg-IP13550-Ag-2 Mouse COX7A2L protein Mouse
GM-Tg-cynog-IP13550-Ag-1/ GM-Tg-cynog-IP13550-Ag-2 Cynomolgus/Rhesus macaque COX7A2L protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13550-Ag-1/ GM-Tg-felg-IP13550-Ag-2 Feline COX7A2L protein Feline
GM-Tg-cang-IP13550-Ag-1/ GM-Tg-cang-IP13550-Ag-2 Canine COX7A2L protein Canine
GM-Tg-bovg-IP13550-Ag-1/ GM-Tg-bovg-IP13550-Ag-2 Bovine COX7A2L protein Bovine
GM-Tg-equg-IP13550-Ag-1/ GM-Tg-equg-IP13550-Ag-2 Equine COX7A2L protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13550-Ag-1/ GM-Tg-hg-IP13550-Ag-2; GM-Tg-rg-IP13550-Ag-1/ GM-Tg-rg-IP13550-Ag-2;
GM-Tg-mg-IP13550-Ag-1/ GM-Tg-mg-IP13550-Ag-2; GM-Tg-cynog-IP13550-Ag-1/ GM-Tg-cynog-IP13550-Ag-2;
GM-Tg-felg-IP13550-Ag-1/ GM-Tg-felg-IP13550-Ag-2; GM-Tg-cang-IP13550-Ag-1/ GM-Tg-cang-IP13550-Ag-2;
GM-Tg-bovg-IP13550-Ag-1/ GM-Tg-bovg-IP13550-Ag-2; GM-Tg-equg-IP13550-Ag-1/ GM-Tg-equg-IP13550-Ag-2
Products Name COX7A2L protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name COX7A2L
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COX7A2L protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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