Recombinant multi-species SMC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMC3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]
The Alternative Names of target: BAM,BMH,Bamacan,Basement membrane-associated chondroitin proteoglycan (Bamacan),CDLS3,CSPG6,Chondroitin sulfate proteoglycan 6,Chromosome-associated polypeptide (hCAP),Cspg6,HCAP,Mmip1,SMC protein 3,SMC-3,SMC3,SMC3L1,Smc3,SmcD,Structural maintenance of chromosomes protein 3,bamacan
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP13503-Ag-1/ GM-Tg-hg-IP13503-Ag-2 | Human SMC3 protein | Human |
| GM-Tg-rg-IP13503-Ag-1/ GM-Tg-rg-IP13503-Ag-2 | Rat SMC3 protein | Rat |
| GM-Tg-mg-IP13503-Ag-1/ GM-Tg-mg-IP13503-Ag-2 | Mouse SMC3 protein | Mouse |
| GM-Tg-cynog-IP13503-Ag-1/ GM-Tg-cynog-IP13503-Ag-2 | Cynomolgus/Rhesus macaque SMC3 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP13503-Ag-1/ GM-Tg-felg-IP13503-Ag-2 | Feline SMC3 protein | Feline |
| GM-Tg-cang-IP13503-Ag-1/ GM-Tg-cang-IP13503-Ag-2 | Canine SMC3 protein | Canine |
| GM-Tg-bovg-IP13503-Ag-1/ GM-Tg-bovg-IP13503-Ag-2 | Bovine SMC3 protein | Bovine |
| GM-Tg-equg-IP13503-Ag-1/ GM-Tg-equg-IP13503-Ag-2 | Equine SMC3 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP13503-Ag-1/ GM-Tg-hg-IP13503-Ag-2;
GM-Tg-rg-IP13503-Ag-1/ GM-Tg-rg-IP13503-Ag-2;
GM-Tg-mg-IP13503-Ag-1/ GM-Tg-mg-IP13503-Ag-2; GM-Tg-cynog-IP13503-Ag-1/ GM-Tg-cynog-IP13503-Ag-2; GM-Tg-felg-IP13503-Ag-1/ GM-Tg-felg-IP13503-Ag-2; GM-Tg-cang-IP13503-Ag-1/ GM-Tg-cang-IP13503-Ag-2; GM-Tg-bovg-IP13503-Ag-1/ GM-Tg-bovg-IP13503-Ag-2; GM-Tg-equg-IP13503-Ag-1/ GM-Tg-equg-IP13503-Ag-2 |
| Products Name | SMC3 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | SMC3 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMC3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.