Recombinant multi-species UBC12/UBE2M protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UBC12/UBE2M protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2510040H03Rik,NEDD8 carrier protein,NEDD8-conjugating enzyme Ubc12,UBC-RS2,UBC12,UBE2M,Ubc-rs2,Ube2m,Ubiquitin-conjugating enzyme E2 M,hUbc12

Target products collectionGo to UBC12/UBE2M products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13416-Ag-1/ GM-Tg-hg-IP13416-Ag-2 Human UBC12/UBE2M protein Human
GM-Tg-rg-IP13416-Ag-1/ GM-Tg-rg-IP13416-Ag-2 Rat UBC12/UBE2M protein Rat
GM-Tg-mg-IP13416-Ag-1/ GM-Tg-mg-IP13416-Ag-2 Mouse UBC12/UBE2M protein Mouse
GM-Tg-cynog-IP13416-Ag-1/ GM-Tg-cynog-IP13416-Ag-2 Cynomolgus/Rhesus macaque UBC12/UBE2M protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13416-Ag-1/ GM-Tg-felg-IP13416-Ag-2 Feline UBC12/UBE2M protein Feline
GM-Tg-cang-IP13416-Ag-1/ GM-Tg-cang-IP13416-Ag-2 Canine UBC12/UBE2M protein Canine
GM-Tg-bovg-IP13416-Ag-1/ GM-Tg-bovg-IP13416-Ag-2 Bovine UBC12/UBE2M protein Bovine
GM-Tg-equg-IP13416-Ag-1/ GM-Tg-equg-IP13416-Ag-2 Equine UBC12/UBE2M protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13416-Ag-1/ GM-Tg-hg-IP13416-Ag-2; GM-Tg-rg-IP13416-Ag-1/ GM-Tg-rg-IP13416-Ag-2;
GM-Tg-mg-IP13416-Ag-1/ GM-Tg-mg-IP13416-Ag-2; GM-Tg-cynog-IP13416-Ag-1/ GM-Tg-cynog-IP13416-Ag-2;
GM-Tg-felg-IP13416-Ag-1/ GM-Tg-felg-IP13416-Ag-2; GM-Tg-cang-IP13416-Ag-1/ GM-Tg-cang-IP13416-Ag-2;
GM-Tg-bovg-IP13416-Ag-1/ GM-Tg-bovg-IP13416-Ag-2; GM-Tg-equg-IP13416-Ag-1/ GM-Tg-equg-IP13416-Ag-2
Products Name UBC12/UBE2M protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name UBC12/UBE2M
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UBC12/UBE2M protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.