Recombinant multi-species PCDHA7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCDHA7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: PCDHA7,Protocadherin alpha-7,PCDH-alpha-7,CNR4,CNRN4,CNRS4,CRNR4,PCDH-ALPHA7
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1334-Ab-1/ GM-Tg-hg-IP1334-Ab-2 | Human PCDHA7 protein | Human |
GM-Tg-rg-IP1334-Ab-1/ GM-Tg-rg-IP1334-Ab-2 | Rat PCDHA7 protein | Rat |
GM-Tg-mg-IP1334-Ab-1/ GM-Tg-mg-IP1334-Ab-2 | Mouse PCDHA7 protein | Mouse |
GM-Tg-cynog-IP1334-Ab-1/ GM-Tg-cynog-IP1334-Ab-2 | Cynomolgus/Rhesus macaque PCDHA7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1334-Ab-1/ GM-Tg-felg-IP1334-Ab-2 | Feline PCDHA7 protein | Feline |
GM-Tg-cang-IP1334-Ab-1/ GM-Tg-cang-IP1334-Ab-2 | Canine PCDHA7 protein | Canine |
GM-Tg-bovg-IP1334-Ab-1/ GM-Tg-bovg-IP1334-Ab-2 | Bovine PCDHA7 protein | Bovine |
GM-Tg-equg-IP1334-Ab-1/ GM-Tg-equg-IP1334-Ab-2 | Equine PCDHA7 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP1334-Ab-1/ GM-Tg-hg-IP1334-Ab-2;
GM-Tg-rg-IP1334-Ab-1/ GM-Tg-rg-IP1334-Ab-2;
GM-Tg-mg-IP1334-Ab-1/ GM-Tg-mg-IP1334-Ab-2; GM-Tg-cynog-IP1334-Ab-1/ GM-Tg-cynog-IP1334-Ab-2; GM-Tg-felg-IP1334-Ab-1/ GM-Tg-felg-IP1334-Ab-2; GM-Tg-cang-IP1334-Ab-1/ GM-Tg-cang-IP1334-Ab-2; GM-Tg-bovg-IP1334-Ab-1/ GM-Tg-bovg-IP1334-Ab-2; GM-Tg-equg-IP1334-Ab-1/ GM-Tg-equg-IP1334-Ab-2 |
Products Name | PCDHA7 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | PCDHA7 |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCDHA7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
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characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.