Recombinant multi-species PCDHA5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCDHA5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CNR6,CNRN6,CNRS6,CRNR6,Cnr6,Crnr6,LOC478037,PCDH-ALPHA5,PCDH-alpha-5,PCDHA5,Pcdha5,Protocadherin alpha-5

Target products collectionGo to PCDHA5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1333-Ag-1/ GM-Tg-hg-IP1333-Ag-2 Human PCDHA5 protein Human
GM-Tg-rg-IP1333-Ag-1/ GM-Tg-rg-IP1333-Ag-2 Rat PCDHA5 protein Rat
GM-Tg-mg-IP1333-Ag-1/ GM-Tg-mg-IP1333-Ag-2 Mouse PCDHA5 protein Mouse
GM-Tg-cynog-IP1333-Ag-1/ GM-Tg-cynog-IP1333-Ag-2 Cynomolgus/Rhesus macaque PCDHA5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1333-Ag-1/ GM-Tg-felg-IP1333-Ag-2 Feline PCDHA5 protein Feline
GM-Tg-cang-IP1333-Ag-1/ GM-Tg-cang-IP1333-Ag-2 Canine PCDHA5 protein Canine
GM-Tg-bovg-IP1333-Ag-1/ GM-Tg-bovg-IP1333-Ag-2 Bovine PCDHA5 protein Bovine
GM-Tg-equg-IP1333-Ag-1/ GM-Tg-equg-IP1333-Ag-2 Equine PCDHA5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1333-Ag-1/ GM-Tg-hg-IP1333-Ag-2; GM-Tg-rg-IP1333-Ag-1/ GM-Tg-rg-IP1333-Ag-2;
GM-Tg-mg-IP1333-Ag-1/ GM-Tg-mg-IP1333-Ag-2; GM-Tg-cynog-IP1333-Ag-1/ GM-Tg-cynog-IP1333-Ag-2;
GM-Tg-felg-IP1333-Ag-1/ GM-Tg-felg-IP1333-Ag-2; GM-Tg-cang-IP1333-Ag-1/ GM-Tg-cang-IP1333-Ag-2;
GM-Tg-bovg-IP1333-Ag-1/ GM-Tg-bovg-IP1333-Ag-2; GM-Tg-equg-IP1333-Ag-1/ GM-Tg-equg-IP1333-Ag-2
Products Name PCDHA5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PCDHA5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCDHA5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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