Recombinant multi-species GANP/MCM3AP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GANP/MCM3AP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014]
The Alternative Names of target: 80 kDa MCM3-associated protein,GANP,Germinal-center associated nuclear protein,MAP80,MCM3 acetylating protein (MCM3AP),MCM3 acetyltransferase,MCM3AP,Mcm3ap,PNRIID,SAC3

Target products collectionGo to GANP/MCM3AP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13306-Ag-1/ GM-Tg-hg-IP13306-Ag-2 Human GANP/MCM3AP protein Human
GM-Tg-rg-IP13306-Ag-1/ GM-Tg-rg-IP13306-Ag-2 Rat GANP/MCM3AP protein Rat
GM-Tg-mg-IP13306-Ag-1/ GM-Tg-mg-IP13306-Ag-2 Mouse GANP/MCM3AP protein Mouse
GM-Tg-cynog-IP13306-Ag-1/ GM-Tg-cynog-IP13306-Ag-2 Cynomolgus/Rhesus macaque GANP/MCM3AP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13306-Ag-1/ GM-Tg-felg-IP13306-Ag-2 Feline GANP/MCM3AP protein Feline
GM-Tg-cang-IP13306-Ag-1/ GM-Tg-cang-IP13306-Ag-2 Canine GANP/MCM3AP protein Canine
GM-Tg-bovg-IP13306-Ag-1/ GM-Tg-bovg-IP13306-Ag-2 Bovine GANP/MCM3AP protein Bovine
GM-Tg-equg-IP13306-Ag-1/ GM-Tg-equg-IP13306-Ag-2 Equine GANP/MCM3AP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13306-Ag-1/ GM-Tg-hg-IP13306-Ag-2; GM-Tg-rg-IP13306-Ag-1/ GM-Tg-rg-IP13306-Ag-2;
GM-Tg-mg-IP13306-Ag-1/ GM-Tg-mg-IP13306-Ag-2; GM-Tg-cynog-IP13306-Ag-1/ GM-Tg-cynog-IP13306-Ag-2;
GM-Tg-felg-IP13306-Ag-1/ GM-Tg-felg-IP13306-Ag-2; GM-Tg-cang-IP13306-Ag-1/ GM-Tg-cang-IP13306-Ag-2;
GM-Tg-bovg-IP13306-Ag-1/ GM-Tg-bovg-IP13306-Ag-2; GM-Tg-equg-IP13306-Ag-1/ GM-Tg-equg-IP13306-Ag-2
Products Name GANP/MCM3AP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GANP/MCM3AP
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GANP/MCM3AP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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