Recombinant multi-species PER2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PER2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]
The Alternative Names of target: Circadian clock protein PERIOD 2,FASPS,FASPS1,PER2,Per2,Period circadian protein homolog 2,hPER2,mKIAA0347,mPer2,rPER2

Target products collectionGo to PER2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13296-Ag-1/ GM-Tg-hg-IP13296-Ag-2 Human PER2 protein Human
GM-Tg-rg-IP13296-Ag-1/ GM-Tg-rg-IP13296-Ag-2 Rat PER2 protein Rat
GM-Tg-mg-IP13296-Ag-1/ GM-Tg-mg-IP13296-Ag-2 Mouse PER2 protein Mouse
GM-Tg-cynog-IP13296-Ag-1/ GM-Tg-cynog-IP13296-Ag-2 Cynomolgus/Rhesus macaque PER2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13296-Ag-1/ GM-Tg-felg-IP13296-Ag-2 Feline PER2 protein Feline
GM-Tg-cang-IP13296-Ag-1/ GM-Tg-cang-IP13296-Ag-2 Canine PER2 protein Canine
GM-Tg-bovg-IP13296-Ag-1/ GM-Tg-bovg-IP13296-Ag-2 Bovine PER2 protein Bovine
GM-Tg-equg-IP13296-Ag-1/ GM-Tg-equg-IP13296-Ag-2 Equine PER2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13296-Ag-1/ GM-Tg-hg-IP13296-Ag-2; GM-Tg-rg-IP13296-Ag-1/ GM-Tg-rg-IP13296-Ag-2;
GM-Tg-mg-IP13296-Ag-1/ GM-Tg-mg-IP13296-Ag-2; GM-Tg-cynog-IP13296-Ag-1/ GM-Tg-cynog-IP13296-Ag-2;
GM-Tg-felg-IP13296-Ag-1/ GM-Tg-felg-IP13296-Ag-2; GM-Tg-cang-IP13296-Ag-1/ GM-Tg-cang-IP13296-Ag-2;
GM-Tg-bovg-IP13296-Ag-1/ GM-Tg-bovg-IP13296-Ag-2; GM-Tg-equg-IP13296-Ag-1/ GM-Tg-equg-IP13296-Ag-2
Products Name PER2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PER2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PER2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.