Recombinant multi-species ALDH1A2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALDH1A2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
The Alternative Names of target: ALDH1A2,Aldehyde dehydrogenase family 1 member A2 (ALDH1A2),Aldh1a2,Aldh1a7,DIH4,RALDH 2,RALDH(II),RALDH2,RALDH2-T,RalDH2,Raldh-2,Raldh1,Raldh2,Retinal dehydrogenase 2,Retinaldehyde-specific dehydrogenase type 2 (RALDH(II))
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP13292-Ag-1/ GM-Tg-hg-IP13292-Ag-2 | Human ALDH1A2 protein | Human |
| GM-Tg-rg-IP13292-Ag-1/ GM-Tg-rg-IP13292-Ag-2 | Rat ALDH1A2 protein | Rat |
| GM-Tg-mg-IP13292-Ag-1/ GM-Tg-mg-IP13292-Ag-2 | Mouse ALDH1A2 protein | Mouse |
| GM-Tg-cynog-IP13292-Ag-1/ GM-Tg-cynog-IP13292-Ag-2 | Cynomolgus/Rhesus macaque ALDH1A2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP13292-Ag-1/ GM-Tg-felg-IP13292-Ag-2 | Feline ALDH1A2 protein | Feline |
| GM-Tg-cang-IP13292-Ag-1/ GM-Tg-cang-IP13292-Ag-2 | Canine ALDH1A2 protein | Canine |
| GM-Tg-bovg-IP13292-Ag-1/ GM-Tg-bovg-IP13292-Ag-2 | Bovine ALDH1A2 protein | Bovine |
| GM-Tg-equg-IP13292-Ag-1/ GM-Tg-equg-IP13292-Ag-2 | Equine ALDH1A2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP13292-Ag-1/ GM-Tg-hg-IP13292-Ag-2;
GM-Tg-rg-IP13292-Ag-1/ GM-Tg-rg-IP13292-Ag-2;
GM-Tg-mg-IP13292-Ag-1/ GM-Tg-mg-IP13292-Ag-2; GM-Tg-cynog-IP13292-Ag-1/ GM-Tg-cynog-IP13292-Ag-2; GM-Tg-felg-IP13292-Ag-1/ GM-Tg-felg-IP13292-Ag-2; GM-Tg-cang-IP13292-Ag-1/ GM-Tg-cang-IP13292-Ag-2; GM-Tg-bovg-IP13292-Ag-1/ GM-Tg-bovg-IP13292-Ag-2; GM-Tg-equg-IP13292-Ag-1/ GM-Tg-equg-IP13292-Ag-2 |
| Products Name | ALDH1A2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | ALDH1A2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALDH1A2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
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myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.