Recombinant multi-species SOCS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
The Alternative Names of target: 8030460M17,CIS2,Cish2,Cytokine-inducible SH2 protein 2 (CIS-2),D130043N08Rik,JAB,SOCS-2,SOCS2,SSI-2,SSI2,STAT-induced STAT inhibitor 2 (SSI-2),STATI2,Socs-2,Socs2,Suppressor of cytokine signaling 2,hg

Target products collectionGo to SOCS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13288-Ag-1/ GM-Tg-hg-IP13288-Ag-2 Human SOCS2 protein Human
GM-Tg-rg-IP13288-Ag-1/ GM-Tg-rg-IP13288-Ag-2 Rat SOCS2 protein Rat
GM-Tg-mg-IP13288-Ag-1/ GM-Tg-mg-IP13288-Ag-2 Mouse SOCS2 protein Mouse
GM-Tg-cynog-IP13288-Ag-1/ GM-Tg-cynog-IP13288-Ag-2 Cynomolgus/Rhesus macaque SOCS2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13288-Ag-1/ GM-Tg-felg-IP13288-Ag-2 Feline SOCS2 protein Feline
GM-Tg-cang-IP13288-Ag-1/ GM-Tg-cang-IP13288-Ag-2 Canine SOCS2 protein Canine
GM-Tg-bovg-IP13288-Ag-1/ GM-Tg-bovg-IP13288-Ag-2 Bovine SOCS2 protein Bovine
GM-Tg-equg-IP13288-Ag-1/ GM-Tg-equg-IP13288-Ag-2 Equine SOCS2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13288-Ag-1/ GM-Tg-hg-IP13288-Ag-2; GM-Tg-rg-IP13288-Ag-1/ GM-Tg-rg-IP13288-Ag-2;
GM-Tg-mg-IP13288-Ag-1/ GM-Tg-mg-IP13288-Ag-2; GM-Tg-cynog-IP13288-Ag-1/ GM-Tg-cynog-IP13288-Ag-2;
GM-Tg-felg-IP13288-Ag-1/ GM-Tg-felg-IP13288-Ag-2; GM-Tg-cang-IP13288-Ag-1/ GM-Tg-cang-IP13288-Ag-2;
GM-Tg-bovg-IP13288-Ag-1/ GM-Tg-bovg-IP13288-Ag-2; GM-Tg-equg-IP13288-Ag-1/ GM-Tg-equg-IP13288-Ag-2
Products Name SOCS2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SOCS2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOCS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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