Recombinant multi-species CCBL1/KYAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCBL1/KYAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2010009K05Rik,CCBL1,Ccbl1,Cysteine-S-conjugate beta-lyase,GTK,Glutamine transaminase K (GTK),Glutamine--phenylpyruvate transaminase,Gtk,KAT1,KATI,KYAT1,Kat1,KatI,Kyat1,Kynurenine aminotransferase 1,Kynurenine aminotransferase I (KATI),Kynurenine--oxoglutarate transaminase 1,Kynurenine--oxoglutarate transaminase I
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP13286-Ag-1/ GM-Tg-hg-IP13286-Ag-2 | Human CCBL1/KYAT1 protein | Human |
| GM-Tg-rg-IP13286-Ag-1/ GM-Tg-rg-IP13286-Ag-2 | Rat CCBL1/KYAT1 protein | Rat |
| GM-Tg-mg-IP13286-Ag-1/ GM-Tg-mg-IP13286-Ag-2 | Mouse CCBL1/KYAT1 protein | Mouse |
| GM-Tg-cynog-IP13286-Ag-1/ GM-Tg-cynog-IP13286-Ag-2 | Cynomolgus/Rhesus macaque CCBL1/KYAT1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP13286-Ag-1/ GM-Tg-felg-IP13286-Ag-2 | Feline CCBL1/KYAT1 protein | Feline |
| GM-Tg-cang-IP13286-Ag-1/ GM-Tg-cang-IP13286-Ag-2 | Canine CCBL1/KYAT1 protein | Canine |
| GM-Tg-bovg-IP13286-Ag-1/ GM-Tg-bovg-IP13286-Ag-2 | Bovine CCBL1/KYAT1 protein | Bovine |
| GM-Tg-equg-IP13286-Ag-1/ GM-Tg-equg-IP13286-Ag-2 | Equine CCBL1/KYAT1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP13286-Ag-1/ GM-Tg-hg-IP13286-Ag-2;
GM-Tg-rg-IP13286-Ag-1/ GM-Tg-rg-IP13286-Ag-2;
GM-Tg-mg-IP13286-Ag-1/ GM-Tg-mg-IP13286-Ag-2; GM-Tg-cynog-IP13286-Ag-1/ GM-Tg-cynog-IP13286-Ag-2; GM-Tg-felg-IP13286-Ag-1/ GM-Tg-felg-IP13286-Ag-2; GM-Tg-cang-IP13286-Ag-1/ GM-Tg-cang-IP13286-Ag-2; GM-Tg-bovg-IP13286-Ag-1/ GM-Tg-bovg-IP13286-Ag-2; GM-Tg-equg-IP13286-Ag-1/ GM-Tg-equg-IP13286-Ag-2 |
| Products Name | CCBL1/KYAT1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CCBL1/KYAT1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCBL1/KYAT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.