Recombinant multi-species BANF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BANF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009]
The Alternative Names of target: BAF,BANF1,BCRP1,Baf,Banf1,Barrier-to-autointegration factor,Bcrp1,Breakpoint cluster region protein 1,D14S1460,L2bp1,L2bp1/Baf,NGPS

Target products collectionGo to BANF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13282-Ag-1/ GM-Tg-hg-IP13282-Ag-2 Human BANF1 protein Human
GM-Tg-rg-IP13282-Ag-1/ GM-Tg-rg-IP13282-Ag-2 Rat BANF1 protein Rat
GM-Tg-mg-IP13282-Ag-1/ GM-Tg-mg-IP13282-Ag-2 Mouse BANF1 protein Mouse
GM-Tg-cynog-IP13282-Ag-1/ GM-Tg-cynog-IP13282-Ag-2 Cynomolgus/Rhesus macaque BANF1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13282-Ag-1/ GM-Tg-felg-IP13282-Ag-2 Feline BANF1 protein Feline
GM-Tg-cang-IP13282-Ag-1/ GM-Tg-cang-IP13282-Ag-2 Canine BANF1 protein Canine
GM-Tg-bovg-IP13282-Ag-1/ GM-Tg-bovg-IP13282-Ag-2 Bovine BANF1 protein Bovine
GM-Tg-equg-IP13282-Ag-1/ GM-Tg-equg-IP13282-Ag-2 Equine BANF1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13282-Ag-1/ GM-Tg-hg-IP13282-Ag-2; GM-Tg-rg-IP13282-Ag-1/ GM-Tg-rg-IP13282-Ag-2;
GM-Tg-mg-IP13282-Ag-1/ GM-Tg-mg-IP13282-Ag-2; GM-Tg-cynog-IP13282-Ag-1/ GM-Tg-cynog-IP13282-Ag-2;
GM-Tg-felg-IP13282-Ag-1/ GM-Tg-felg-IP13282-Ag-2; GM-Tg-cang-IP13282-Ag-1/ GM-Tg-cang-IP13282-Ag-2;
GM-Tg-bovg-IP13282-Ag-1/ GM-Tg-bovg-IP13282-Ag-2; GM-Tg-equg-IP13282-Ag-1/ GM-Tg-equg-IP13282-Ag-2
Products Name BANF1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BANF1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BANF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.