Recombinant multi-species ACTN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ACTN2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
The Alternative Names of target: 1110008F24Rik,ACTN2,Actn2,Alpha-actinin skeletal muscle isoform 2,Alpha-actinin-2,CMD1AA,CMH23,CMYO8,CMYP8,F-actin cross-linking protein,MPD6,MYOCOZ

Target products collectionGo to ACTN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13278-Ag-1/ GM-Tg-hg-IP13278-Ag-2 Human ACTN2 protein Human
GM-Tg-rg-IP13278-Ag-1/ GM-Tg-rg-IP13278-Ag-2 Rat ACTN2 protein Rat
GM-Tg-mg-IP13278-Ag-1/ GM-Tg-mg-IP13278-Ag-2 Mouse ACTN2 protein Mouse
GM-Tg-cynog-IP13278-Ag-1/ GM-Tg-cynog-IP13278-Ag-2 Cynomolgus/Rhesus macaque ACTN2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13278-Ag-1/ GM-Tg-felg-IP13278-Ag-2 Feline ACTN2 protein Feline
GM-Tg-cang-IP13278-Ag-1/ GM-Tg-cang-IP13278-Ag-2 Canine ACTN2 protein Canine
GM-Tg-bovg-IP13278-Ag-1/ GM-Tg-bovg-IP13278-Ag-2 Bovine ACTN2 protein Bovine
GM-Tg-equg-IP13278-Ag-1/ GM-Tg-equg-IP13278-Ag-2 Equine ACTN2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13278-Ag-1/ GM-Tg-hg-IP13278-Ag-2; GM-Tg-rg-IP13278-Ag-1/ GM-Tg-rg-IP13278-Ag-2;
GM-Tg-mg-IP13278-Ag-1/ GM-Tg-mg-IP13278-Ag-2; GM-Tg-cynog-IP13278-Ag-1/ GM-Tg-cynog-IP13278-Ag-2;
GM-Tg-felg-IP13278-Ag-1/ GM-Tg-felg-IP13278-Ag-2; GM-Tg-cang-IP13278-Ag-1/ GM-Tg-cang-IP13278-Ag-2;
GM-Tg-bovg-IP13278-Ag-1/ GM-Tg-bovg-IP13278-Ag-2; GM-Tg-equg-IP13278-Ag-1/ GM-Tg-equg-IP13278-Ag-2
Products Name ACTN2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ACTN2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ACTN2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.