Recombinant multi-species PBXIP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PBXIP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined. [provided by RefSeq, Dec 2015]
The Alternative Names of target: PBXIP1,Pre-B-cell leukemia transcription factor-interacting protein 1,Hematopoietic PBX-interacting protein,HPIP

Target products collectionGo to PBXIP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1327-Ab-1/ GM-Tg-hg-IP1327-Ab-2 Human PBXIP1 protein Human
GM-Tg-rg-IP1327-Ab-1/ GM-Tg-rg-IP1327-Ab-2 Rat PBXIP1 protein Rat
GM-Tg-mg-IP1327-Ab-1/ GM-Tg-mg-IP1327-Ab-2 Mouse PBXIP1 protein Mouse
GM-Tg-cynog-IP1327-Ab-1/ GM-Tg-cynog-IP1327-Ab-2 Cynomolgus/Rhesus macaque PBXIP1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1327-Ab-1/ GM-Tg-felg-IP1327-Ab-2 Feline PBXIP1 protein Feline
GM-Tg-cang-IP1327-Ab-1/ GM-Tg-cang-IP1327-Ab-2 Canine PBXIP1 protein Canine
GM-Tg-bovg-IP1327-Ab-1/ GM-Tg-bovg-IP1327-Ab-2 Bovine PBXIP1 protein Bovine
GM-Tg-equg-IP1327-Ab-1/ GM-Tg-equg-IP1327-Ab-2 Equine PBXIP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1327-Ab-1/ GM-Tg-hg-IP1327-Ab-2; GM-Tg-rg-IP1327-Ab-1/ GM-Tg-rg-IP1327-Ab-2;
GM-Tg-mg-IP1327-Ab-1/ GM-Tg-mg-IP1327-Ab-2; GM-Tg-cynog-IP1327-Ab-1/ GM-Tg-cynog-IP1327-Ab-2;
GM-Tg-felg-IP1327-Ab-1/ GM-Tg-felg-IP1327-Ab-2; GM-Tg-cang-IP1327-Ab-1/ GM-Tg-cang-IP1327-Ab-2;
GM-Tg-bovg-IP1327-Ab-1/ GM-Tg-bovg-IP1327-Ab-2; GM-Tg-equg-IP1327-Ab-1/ GM-Tg-equg-IP1327-Ab-2
Products Name PBXIP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PBXIP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PBXIP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.