Recombinant multi-species GBF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GBF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
The Alternative Names of target: 1700083E03Rik,ARF1GEF,BFA-resistant GEF 1,CMT2GG,CMTDI2,CMTDIA,GBF1,Gbf1,Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1,RGD1307160,mKIAA0248
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP13264-Ag-1/ GM-Tg-hg-IP13264-Ag-2 | Human GBF1 protein | Human |
| GM-Tg-rg-IP13264-Ag-1/ GM-Tg-rg-IP13264-Ag-2 | Rat GBF1 protein | Rat |
| GM-Tg-mg-IP13264-Ag-1/ GM-Tg-mg-IP13264-Ag-2 | Mouse GBF1 protein | Mouse |
| GM-Tg-cynog-IP13264-Ag-1/ GM-Tg-cynog-IP13264-Ag-2 | Cynomolgus/Rhesus macaque GBF1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP13264-Ag-1/ GM-Tg-felg-IP13264-Ag-2 | Feline GBF1 protein | Feline |
| GM-Tg-cang-IP13264-Ag-1/ GM-Tg-cang-IP13264-Ag-2 | Canine GBF1 protein | Canine |
| GM-Tg-bovg-IP13264-Ag-1/ GM-Tg-bovg-IP13264-Ag-2 | Bovine GBF1 protein | Bovine |
| GM-Tg-equg-IP13264-Ag-1/ GM-Tg-equg-IP13264-Ag-2 | Equine GBF1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP13264-Ag-1/ GM-Tg-hg-IP13264-Ag-2;
GM-Tg-rg-IP13264-Ag-1/ GM-Tg-rg-IP13264-Ag-2;
GM-Tg-mg-IP13264-Ag-1/ GM-Tg-mg-IP13264-Ag-2; GM-Tg-cynog-IP13264-Ag-1/ GM-Tg-cynog-IP13264-Ag-2; GM-Tg-felg-IP13264-Ag-1/ GM-Tg-felg-IP13264-Ag-2; GM-Tg-cang-IP13264-Ag-1/ GM-Tg-cang-IP13264-Ag-2; GM-Tg-bovg-IP13264-Ag-1/ GM-Tg-bovg-IP13264-Ag-2; GM-Tg-equg-IP13264-Ag-1/ GM-Tg-equg-IP13264-Ag-2 |
| Products Name | GBF1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | GBF1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GBF1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.