Recombinant multi-species DNAH11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNAH11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]
The Alternative Names of target: Axonemal beta dynein heavy chain 11,Bv1,CILD7,Ciliary dynein heavy chain 11,DNAH11,DNAHBL,DNAHC11,DNHBL,DPL11,Dnah11,Dnahc11,Dynein axonemal heavy chain 11,avc4,b2b1203Clo,b2b1279Clo,b2b1289Clo,b2b1727Clo,b2b598Clo,iv,lrd

Target products collectionGo to DNAH11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13253-Ag-1/ GM-Tg-hg-IP13253-Ag-2 Human DNAH11 protein Human
GM-Tg-rg-IP13253-Ag-1/ GM-Tg-rg-IP13253-Ag-2 Rat DNAH11 protein Rat
GM-Tg-mg-IP13253-Ag-1/ GM-Tg-mg-IP13253-Ag-2 Mouse DNAH11 protein Mouse
GM-Tg-cynog-IP13253-Ag-1/ GM-Tg-cynog-IP13253-Ag-2 Cynomolgus/Rhesus macaque DNAH11 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13253-Ag-1/ GM-Tg-felg-IP13253-Ag-2 Feline DNAH11 protein Feline
GM-Tg-cang-IP13253-Ag-1/ GM-Tg-cang-IP13253-Ag-2 Canine DNAH11 protein Canine
GM-Tg-bovg-IP13253-Ag-1/ GM-Tg-bovg-IP13253-Ag-2 Bovine DNAH11 protein Bovine
GM-Tg-equg-IP13253-Ag-1/ GM-Tg-equg-IP13253-Ag-2 Equine DNAH11 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13253-Ag-1/ GM-Tg-hg-IP13253-Ag-2; GM-Tg-rg-IP13253-Ag-1/ GM-Tg-rg-IP13253-Ag-2;
GM-Tg-mg-IP13253-Ag-1/ GM-Tg-mg-IP13253-Ag-2; GM-Tg-cynog-IP13253-Ag-1/ GM-Tg-cynog-IP13253-Ag-2;
GM-Tg-felg-IP13253-Ag-1/ GM-Tg-felg-IP13253-Ag-2; GM-Tg-cang-IP13253-Ag-1/ GM-Tg-cang-IP13253-Ag-2;
GM-Tg-bovg-IP13253-Ag-1/ GM-Tg-bovg-IP13253-Ag-2; GM-Tg-equg-IP13253-Ag-1/ GM-Tg-equg-IP13253-Ag-2
Products Name DNAH11 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DNAH11
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNAH11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.