Recombinant multi-species HAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]
The Alternative Names of target: 2410071B14Rik,HAT1,Hat-1,Hat1,Histone acetyltransferase 1,Histone acetyltransferase type B catalytic subunit,KAT1

Target products collectionGo to HAT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13118-Ag-1/ GM-Tg-hg-IP13118-Ag-2 Human HAT1 protein Human
GM-Tg-rg-IP13118-Ag-1/ GM-Tg-rg-IP13118-Ag-2 Rat HAT1 protein Rat
GM-Tg-mg-IP13118-Ag-1/ GM-Tg-mg-IP13118-Ag-2 Mouse HAT1 protein Mouse
GM-Tg-cynog-IP13118-Ag-1/ GM-Tg-cynog-IP13118-Ag-2 Cynomolgus/Rhesus macaque HAT1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13118-Ag-1/ GM-Tg-felg-IP13118-Ag-2 Feline HAT1 protein Feline
GM-Tg-cang-IP13118-Ag-1/ GM-Tg-cang-IP13118-Ag-2 Canine HAT1 protein Canine
GM-Tg-bovg-IP13118-Ag-1/ GM-Tg-bovg-IP13118-Ag-2 Bovine HAT1 protein Bovine
GM-Tg-equg-IP13118-Ag-1/ GM-Tg-equg-IP13118-Ag-2 Equine HAT1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13118-Ag-1/ GM-Tg-hg-IP13118-Ag-2; GM-Tg-rg-IP13118-Ag-1/ GM-Tg-rg-IP13118-Ag-2;
GM-Tg-mg-IP13118-Ag-1/ GM-Tg-mg-IP13118-Ag-2; GM-Tg-cynog-IP13118-Ag-1/ GM-Tg-cynog-IP13118-Ag-2;
GM-Tg-felg-IP13118-Ag-1/ GM-Tg-felg-IP13118-Ag-2; GM-Tg-cang-IP13118-Ag-1/ GM-Tg-cang-IP13118-Ag-2;
GM-Tg-bovg-IP13118-Ag-1/ GM-Tg-bovg-IP13118-Ag-2; GM-Tg-equg-IP13118-Ag-1/ GM-Tg-equg-IP13118-Ag-2
Products Name HAT1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HAT1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HAT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.