Recombinant multi-species IKBKG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IKBKG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016]
The Alternative Names of target: 1110037D23Rik,AMCBX1,EDAID1,FIP-3,FIP3,Fip3p,IKBKG,IKK-gamma,IKKAP1,IKKG,IKK[g],IMD33,IP,IP1,IP2,IPD2,IkB kinase subunit gamma),IkB kinase-associated protein 1 (IKKAP1),Ikbkg,Inhibitor of nuclear factor kappa-B kinase subunit gamma (I-kappa-B kinase subunit gamma,NEMO,NF-kappa-B essential modifier,NF-kappa-B essential modulator,Nemo,SAIDX,ZC2HC9
Go
to IKBKG products collection
>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP13117-Ag-1/ GM-Tg-hg-IP13117-Ag-2 | Human IKBKG protein | Human |
| GM-Tg-rg-IP13117-Ag-1/ GM-Tg-rg-IP13117-Ag-2 | Rat IKBKG protein | Rat |
| GM-Tg-mg-IP13117-Ag-1/ GM-Tg-mg-IP13117-Ag-2 | Mouse IKBKG protein | Mouse |
| GM-Tg-cynog-IP13117-Ag-1/ GM-Tg-cynog-IP13117-Ag-2 | Cynomolgus/Rhesus macaque IKBKG protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP13117-Ag-1/ GM-Tg-felg-IP13117-Ag-2 | Feline IKBKG protein | Feline |
| GM-Tg-cang-IP13117-Ag-1/ GM-Tg-cang-IP13117-Ag-2 | Canine IKBKG protein | Canine |
| GM-Tg-bovg-IP13117-Ag-1/ GM-Tg-bovg-IP13117-Ag-2 | Bovine IKBKG protein | Bovine |
| GM-Tg-equg-IP13117-Ag-1/ GM-Tg-equg-IP13117-Ag-2 | Equine IKBKG protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP13117-Ag-1/ GM-Tg-hg-IP13117-Ag-2;
GM-Tg-rg-IP13117-Ag-1/ GM-Tg-rg-IP13117-Ag-2;
GM-Tg-mg-IP13117-Ag-1/ GM-Tg-mg-IP13117-Ag-2; GM-Tg-cynog-IP13117-Ag-1/ GM-Tg-cynog-IP13117-Ag-2; GM-Tg-felg-IP13117-Ag-1/ GM-Tg-felg-IP13117-Ag-2; GM-Tg-cang-IP13117-Ag-1/ GM-Tg-cang-IP13117-Ag-2; GM-Tg-bovg-IP13117-Ag-1/ GM-Tg-bovg-IP13117-Ag-2; GM-Tg-equg-IP13117-Ag-1/ GM-Tg-equg-IP13117-Ag-2 |
| Products Name | IKBKG protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | IKBKG |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IKBKG protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.