Recombinant multi-species PPP1R15B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP1R15B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions, while the protein coding ORF is expressed at high levels in response to stress. Continual translation of the mRNA under conditions of eukaryotic translation initiation factor 2A inactivation is thought to create a feedback loop for reactivation of the gene during recovery from stress. In addition, it has been shown that this protein plays a role in membrane traffic that is independent of translation and that it is required for exocytosis from erythroleukemia cells. Allelic variants of this gene are associated with microcephaly, short stature, and impaired glucose metabolism. [provided by RefSeq, Feb 2016]
The Alternative Names of target: 1810033K10Rik,C530022L24Rik,CREP,CReP,MSSGM2,PPP1R15B,Ppp1r15b,Protein phosphatase 1 regulatory subunit 15B

Target products collectionGo to PPP1R15B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP13069-Ag-1/ GM-Tg-hg-IP13069-Ag-2 Human PPP1R15B protein Human
GM-Tg-rg-IP13069-Ag-1/ GM-Tg-rg-IP13069-Ag-2 Rat PPP1R15B protein Rat
GM-Tg-mg-IP13069-Ag-1/ GM-Tg-mg-IP13069-Ag-2 Mouse PPP1R15B protein Mouse
GM-Tg-cynog-IP13069-Ag-1/ GM-Tg-cynog-IP13069-Ag-2 Cynomolgus/Rhesus macaque PPP1R15B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP13069-Ag-1/ GM-Tg-felg-IP13069-Ag-2 Feline PPP1R15B protein Feline
GM-Tg-cang-IP13069-Ag-1/ GM-Tg-cang-IP13069-Ag-2 Canine PPP1R15B protein Canine
GM-Tg-bovg-IP13069-Ag-1/ GM-Tg-bovg-IP13069-Ag-2 Bovine PPP1R15B protein Bovine
GM-Tg-equg-IP13069-Ag-1/ GM-Tg-equg-IP13069-Ag-2 Equine PPP1R15B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP13069-Ag-1/ GM-Tg-hg-IP13069-Ag-2; GM-Tg-rg-IP13069-Ag-1/ GM-Tg-rg-IP13069-Ag-2;
GM-Tg-mg-IP13069-Ag-1/ GM-Tg-mg-IP13069-Ag-2; GM-Tg-cynog-IP13069-Ag-1/ GM-Tg-cynog-IP13069-Ag-2;
GM-Tg-felg-IP13069-Ag-1/ GM-Tg-felg-IP13069-Ag-2; GM-Tg-cang-IP13069-Ag-1/ GM-Tg-cang-IP13069-Ag-2;
GM-Tg-bovg-IP13069-Ag-1/ GM-Tg-bovg-IP13069-Ag-2; GM-Tg-equg-IP13069-Ag-1/ GM-Tg-equg-IP13069-Ag-2
Products Name PPP1R15B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PPP1R15B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPP1R15B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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