Recombinant multi-species TRIM63 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TRIM63 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]
The Alternative Names of target: E3 ubiquitin-protein ligase TRIM63,IRF,Iris RING finger protein,MURF1,MURF2,MuRF1,MuRF1),Murf,Murf1,Muscle-specific RING finger protein 1 (MuRF-1,RF1,RING finger protein 28,RING-type E3 ubiquitin transferase TRIM63,RNF28,Rnf28,SMRZ,Striated muscle RING zinc finger protein,TRIM63,Trim63,Tripartite motif-containing protein 63
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP12995-Ag-1/ GM-Tg-hg-IP12995-Ag-2 | Human TRIM63 protein | Human |
| GM-Tg-rg-IP12995-Ag-1/ GM-Tg-rg-IP12995-Ag-2 | Rat TRIM63 protein | Rat |
| GM-Tg-mg-IP12995-Ag-1/ GM-Tg-mg-IP12995-Ag-2 | Mouse TRIM63 protein | Mouse |
| GM-Tg-cynog-IP12995-Ag-1/ GM-Tg-cynog-IP12995-Ag-2 | Cynomolgus/Rhesus macaque TRIM63 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP12995-Ag-1/ GM-Tg-felg-IP12995-Ag-2 | Feline TRIM63 protein | Feline |
| GM-Tg-cang-IP12995-Ag-1/ GM-Tg-cang-IP12995-Ag-2 | Canine TRIM63 protein | Canine |
| GM-Tg-bovg-IP12995-Ag-1/ GM-Tg-bovg-IP12995-Ag-2 | Bovine TRIM63 protein | Bovine |
| GM-Tg-equg-IP12995-Ag-1/ GM-Tg-equg-IP12995-Ag-2 | Equine TRIM63 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP12995-Ag-1/ GM-Tg-hg-IP12995-Ag-2;
GM-Tg-rg-IP12995-Ag-1/ GM-Tg-rg-IP12995-Ag-2;
GM-Tg-mg-IP12995-Ag-1/ GM-Tg-mg-IP12995-Ag-2; GM-Tg-cynog-IP12995-Ag-1/ GM-Tg-cynog-IP12995-Ag-2; GM-Tg-felg-IP12995-Ag-1/ GM-Tg-felg-IP12995-Ag-2; GM-Tg-cang-IP12995-Ag-1/ GM-Tg-cang-IP12995-Ag-2; GM-Tg-bovg-IP12995-Ag-1/ GM-Tg-bovg-IP12995-Ag-2; GM-Tg-equg-IP12995-Ag-1/ GM-Tg-equg-IP12995-Ag-2 |
| Products Name | TRIM63 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | TRIM63 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TRIM63 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.