Recombinant multi-species LC3A/MAP1LC3A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LC3A/MAP1LC3A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis. [provided by RefSeq, Feb 2012]
The Alternative Names of target: 1010001H21Rik,4922501H04Rik,ATG8E,Autophagy-related protein LC3 A,Autophagy-related ubiquitin-like modifier LC3 A,LC3,LC3-I,LC3-II,LC3A,LC3a,MAP1 light chain 3-like protein 1,MAP1A/MAP1B light chain 3 A),MAP1ALC3,MAP1BLC3,MAP1LC3A,Map1lc3a,Microtubule-associated protein 1 light chain 3 alpha,Microtubule-associated proteins 1A/1B light chain 3A (MAP1A/MAP1B LC3 A
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP12966-Ag-1/ GM-Tg-hg-IP12966-Ag-2 | Human LC3A/MAP1LC3A protein | Human |
| GM-Tg-rg-IP12966-Ag-1/ GM-Tg-rg-IP12966-Ag-2 | Rat LC3A/MAP1LC3A protein | Rat |
| GM-Tg-mg-IP12966-Ag-1/ GM-Tg-mg-IP12966-Ag-2 | Mouse LC3A/MAP1LC3A protein | Mouse |
| GM-Tg-cynog-IP12966-Ag-1/ GM-Tg-cynog-IP12966-Ag-2 | Cynomolgus/Rhesus macaque LC3A/MAP1LC3A protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP12966-Ag-1/ GM-Tg-felg-IP12966-Ag-2 | Feline LC3A/MAP1LC3A protein | Feline |
| GM-Tg-cang-IP12966-Ag-1/ GM-Tg-cang-IP12966-Ag-2 | Canine LC3A/MAP1LC3A protein | Canine |
| GM-Tg-bovg-IP12966-Ag-1/ GM-Tg-bovg-IP12966-Ag-2 | Bovine LC3A/MAP1LC3A protein | Bovine |
| GM-Tg-equg-IP12966-Ag-1/ GM-Tg-equg-IP12966-Ag-2 | Equine LC3A/MAP1LC3A protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP12966-Ag-1/ GM-Tg-hg-IP12966-Ag-2;
GM-Tg-rg-IP12966-Ag-1/ GM-Tg-rg-IP12966-Ag-2;
GM-Tg-mg-IP12966-Ag-1/ GM-Tg-mg-IP12966-Ag-2; GM-Tg-cynog-IP12966-Ag-1/ GM-Tg-cynog-IP12966-Ag-2; GM-Tg-felg-IP12966-Ag-1/ GM-Tg-felg-IP12966-Ag-2; GM-Tg-cang-IP12966-Ag-1/ GM-Tg-cang-IP12966-Ag-2; GM-Tg-bovg-IP12966-Ag-1/ GM-Tg-bovg-IP12966-Ag-2; GM-Tg-equg-IP12966-Ag-1/ GM-Tg-equg-IP12966-Ag-2 |
| Products Name | LC3A/MAP1LC3A protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | LC3A/MAP1LC3A |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LC3A/MAP1LC3A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.