Recombinant multi-species CARD11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CARD11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 0610008L17Rik,2410011D02Rik,BENTA,BIMP3,CARD-containing MAGUK protein 1 (Carma 1),CARD11,CARMA1,Card11,Caspase recruitment domain-containing protein 11,IMD11,IMD11A,PPBL

Target products collectionGo to CARD11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12925-Ag-1/ GM-Tg-hg-IP12925-Ag-2 Human CARD11 protein Human
GM-Tg-rg-IP12925-Ag-1/ GM-Tg-rg-IP12925-Ag-2 Rat CARD11 protein Rat
GM-Tg-mg-IP12925-Ag-1/ GM-Tg-mg-IP12925-Ag-2 Mouse CARD11 protein Mouse
GM-Tg-cynog-IP12925-Ag-1/ GM-Tg-cynog-IP12925-Ag-2 Cynomolgus/Rhesus macaque CARD11 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12925-Ag-1/ GM-Tg-felg-IP12925-Ag-2 Feline CARD11 protein Feline
GM-Tg-cang-IP12925-Ag-1/ GM-Tg-cang-IP12925-Ag-2 Canine CARD11 protein Canine
GM-Tg-bovg-IP12925-Ag-1/ GM-Tg-bovg-IP12925-Ag-2 Bovine CARD11 protein Bovine
GM-Tg-equg-IP12925-Ag-1/ GM-Tg-equg-IP12925-Ag-2 Equine CARD11 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12925-Ag-1/ GM-Tg-hg-IP12925-Ag-2; GM-Tg-rg-IP12925-Ag-1/ GM-Tg-rg-IP12925-Ag-2;
GM-Tg-mg-IP12925-Ag-1/ GM-Tg-mg-IP12925-Ag-2; GM-Tg-cynog-IP12925-Ag-1/ GM-Tg-cynog-IP12925-Ag-2;
GM-Tg-felg-IP12925-Ag-1/ GM-Tg-felg-IP12925-Ag-2; GM-Tg-cang-IP12925-Ag-1/ GM-Tg-cang-IP12925-Ag-2;
GM-Tg-bovg-IP12925-Ag-1/ GM-Tg-bovg-IP12925-Ag-2; GM-Tg-equg-IP12925-Ag-1/ GM-Tg-equg-IP12925-Ag-2
Products Name CARD11 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CARD11
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CARD11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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