Recombinant multi-species H4C14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine H4C14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015]
The Alternative Names of target: FO108,H4,H4-16,H4/n,H4C1,H4C11,H4C12,H4C13,H4C14,H4C15,H4C16,H4C2,H4C3,H4C4,H4C5,H4C6,H4C8,H4C9,H4F2,H4FN,HIST2H4,HIST2H4A,Histone H4

Target products collectionGo to H4C14 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12726-Ag-1/ GM-Tg-hg-IP12726-Ag-2 Human H4C14 protein Human
GM-Tg-rg-IP12726-Ag-1/ GM-Tg-rg-IP12726-Ag-2 Rat H4C14 protein Rat
GM-Tg-mg-IP12726-Ag-1/ GM-Tg-mg-IP12726-Ag-2 Mouse H4C14 protein Mouse
GM-Tg-cynog-IP12726-Ag-1/ GM-Tg-cynog-IP12726-Ag-2 Cynomolgus/Rhesus macaque H4C14 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12726-Ag-1/ GM-Tg-felg-IP12726-Ag-2 Feline H4C14 protein Feline
GM-Tg-cang-IP12726-Ag-1/ GM-Tg-cang-IP12726-Ag-2 Canine H4C14 protein Canine
GM-Tg-bovg-IP12726-Ag-1/ GM-Tg-bovg-IP12726-Ag-2 Bovine H4C14 protein Bovine
GM-Tg-equg-IP12726-Ag-1/ GM-Tg-equg-IP12726-Ag-2 Equine H4C14 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12726-Ag-1/ GM-Tg-hg-IP12726-Ag-2; GM-Tg-rg-IP12726-Ag-1/ GM-Tg-rg-IP12726-Ag-2;
GM-Tg-mg-IP12726-Ag-1/ GM-Tg-mg-IP12726-Ag-2; GM-Tg-cynog-IP12726-Ag-1/ GM-Tg-cynog-IP12726-Ag-2;
GM-Tg-felg-IP12726-Ag-1/ GM-Tg-felg-IP12726-Ag-2; GM-Tg-cang-IP12726-Ag-1/ GM-Tg-cang-IP12726-Ag-2;
GM-Tg-bovg-IP12726-Ag-1/ GM-Tg-bovg-IP12726-Ag-2; GM-Tg-equg-IP12726-Ag-1/ GM-Tg-equg-IP12726-Ag-2
Products Name H4C14 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name H4C14
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine H4C14 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.