Recombinant multi-species Histone H4/H4C5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Histone H4/H4C5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
The Alternative Names of target: H4-16,H4/j,H4C1,H4C11,H4C12,H4C13,H4C14,H4C15,H4C16,H4C2,H4C3,H4C4,H4C5,H4C6,H4C8,H4C9,H4FJ,HIST1H4E,Histone H4,TEBIVANED3,TEVANED3

Target products collectionGo to Histone H4/H4C5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12719-Ag-1/ GM-Tg-hg-IP12719-Ag-2 Human Histone H4/H4C5 protein Human
GM-Tg-rg-IP12719-Ag-1/ GM-Tg-rg-IP12719-Ag-2 Rat Histone H4/H4C5 protein Rat
GM-Tg-mg-IP12719-Ag-1/ GM-Tg-mg-IP12719-Ag-2 Mouse Histone H4/H4C5 protein Mouse
GM-Tg-cynog-IP12719-Ag-1/ GM-Tg-cynog-IP12719-Ag-2 Cynomolgus/Rhesus macaque Histone H4/H4C5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12719-Ag-1/ GM-Tg-felg-IP12719-Ag-2 Feline Histone H4/H4C5 protein Feline
GM-Tg-cang-IP12719-Ag-1/ GM-Tg-cang-IP12719-Ag-2 Canine Histone H4/H4C5 protein Canine
GM-Tg-bovg-IP12719-Ag-1/ GM-Tg-bovg-IP12719-Ag-2 Bovine Histone H4/H4C5 protein Bovine
GM-Tg-equg-IP12719-Ag-1/ GM-Tg-equg-IP12719-Ag-2 Equine Histone H4/H4C5 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12719-Ag-1/ GM-Tg-hg-IP12719-Ag-2; GM-Tg-rg-IP12719-Ag-1/ GM-Tg-rg-IP12719-Ag-2;
GM-Tg-mg-IP12719-Ag-1/ GM-Tg-mg-IP12719-Ag-2; GM-Tg-cynog-IP12719-Ag-1/ GM-Tg-cynog-IP12719-Ag-2;
GM-Tg-felg-IP12719-Ag-1/ GM-Tg-felg-IP12719-Ag-2; GM-Tg-cang-IP12719-Ag-1/ GM-Tg-cang-IP12719-Ag-2;
GM-Tg-bovg-IP12719-Ag-1/ GM-Tg-bovg-IP12719-Ag-2; GM-Tg-equg-IP12719-Ag-1/ GM-Tg-equg-IP12719-Ag-2
Products Name Histone H4/H4C5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Histone H4/H4C5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Histone H4/H4C5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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