Recombinant multi-species MXD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MXD3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
The Alternative Names of target: 4631412E13Rik,BHLHC13,Class C basic helix-loop-helix protein 13 (bHLHc13),MAD3,MXD3,MYX,Mad3,Max dimerization protein 3,Max dimerizer 3,Max-associated protein 3,Max-interacting transcriptional repressor MAD3,Mxd3,Myx,bHLHc13

Target products collectionGo to MXD3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12667-Ag-1/ GM-Tg-hg-IP12667-Ag-2 Human MXD3 protein Human
GM-Tg-rg-IP12667-Ag-1/ GM-Tg-rg-IP12667-Ag-2 Rat MXD3 protein Rat
GM-Tg-mg-IP12667-Ag-1/ GM-Tg-mg-IP12667-Ag-2 Mouse MXD3 protein Mouse
GM-Tg-cynog-IP12667-Ag-1/ GM-Tg-cynog-IP12667-Ag-2 Cynomolgus/Rhesus macaque MXD3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12667-Ag-1/ GM-Tg-felg-IP12667-Ag-2 Feline MXD3 protein Feline
GM-Tg-cang-IP12667-Ag-1/ GM-Tg-cang-IP12667-Ag-2 Canine MXD3 protein Canine
GM-Tg-bovg-IP12667-Ag-1/ GM-Tg-bovg-IP12667-Ag-2 Bovine MXD3 protein Bovine
GM-Tg-equg-IP12667-Ag-1/ GM-Tg-equg-IP12667-Ag-2 Equine MXD3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12667-Ag-1/ GM-Tg-hg-IP12667-Ag-2; GM-Tg-rg-IP12667-Ag-1/ GM-Tg-rg-IP12667-Ag-2;
GM-Tg-mg-IP12667-Ag-1/ GM-Tg-mg-IP12667-Ag-2; GM-Tg-cynog-IP12667-Ag-1/ GM-Tg-cynog-IP12667-Ag-2;
GM-Tg-felg-IP12667-Ag-1/ GM-Tg-felg-IP12667-Ag-2; GM-Tg-cang-IP12667-Ag-1/ GM-Tg-cang-IP12667-Ag-2;
GM-Tg-bovg-IP12667-Ag-1/ GM-Tg-bovg-IP12667-Ag-2; GM-Tg-equg-IP12667-Ag-1/ GM-Tg-equg-IP12667-Ag-2
Products Name MXD3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MXD3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MXD3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.