Recombinant multi-species ARID1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARID1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1110030E03Rik,ARID domain-containing protein 1A,ARID1A,AT-rich interactive domain-containing protein 1A,Arid1a,B120,BAF250,BAF250a,BM029,BRG1-associated factor 250 (BAF250),BRG1-associated factor 250a (BAF250A),C1orf4,CSS2,ELD,MRD14,OSA1,Osa homolog 1 (hOSA1),Osa1,P270,SMARCF1,SWI-like protein,SWI/SNF complex protein p270,SWI/SNF-related,Smarcf1,actin-dependent regulator of chromatin subfamily F member 1,hELD,hOSA1,matrix-associated

Target products collectionGo to ARID1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12623-Ag-1/ GM-Tg-hg-IP12623-Ag-2 Human ARID1A protein Human
GM-Tg-rg-IP12623-Ag-1/ GM-Tg-rg-IP12623-Ag-2 Rat ARID1A protein Rat
GM-Tg-mg-IP12623-Ag-1/ GM-Tg-mg-IP12623-Ag-2 Mouse ARID1A protein Mouse
GM-Tg-cynog-IP12623-Ag-1/ GM-Tg-cynog-IP12623-Ag-2 Cynomolgus/Rhesus macaque ARID1A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12623-Ag-1/ GM-Tg-felg-IP12623-Ag-2 Feline ARID1A protein Feline
GM-Tg-cang-IP12623-Ag-1/ GM-Tg-cang-IP12623-Ag-2 Canine ARID1A protein Canine
GM-Tg-bovg-IP12623-Ag-1/ GM-Tg-bovg-IP12623-Ag-2 Bovine ARID1A protein Bovine
GM-Tg-equg-IP12623-Ag-1/ GM-Tg-equg-IP12623-Ag-2 Equine ARID1A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12623-Ag-1/ GM-Tg-hg-IP12623-Ag-2; GM-Tg-rg-IP12623-Ag-1/ GM-Tg-rg-IP12623-Ag-2;
GM-Tg-mg-IP12623-Ag-1/ GM-Tg-mg-IP12623-Ag-2; GM-Tg-cynog-IP12623-Ag-1/ GM-Tg-cynog-IP12623-Ag-2;
GM-Tg-felg-IP12623-Ag-1/ GM-Tg-felg-IP12623-Ag-2; GM-Tg-cang-IP12623-Ag-1/ GM-Tg-cang-IP12623-Ag-2;
GM-Tg-bovg-IP12623-Ag-1/ GM-Tg-bovg-IP12623-Ag-2; GM-Tg-equg-IP12623-Ag-1/ GM-Tg-equg-IP12623-Ag-2
Products Name ARID1A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ARID1A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ARID1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.