Recombinant multi-species PABPN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PABPN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010]
The Alternative Names of target: Nuclear poly(A)-binding protein 1,OPMD,PAB2,PABII,PABP-2,PABP2,PABPN1,Pabp3,Pabpn1,Poly(A)-binding protein 2,Poly(A)-binding protein II (PABII),Polyadenylate-binding nuclear protein 1,Polyadenylate-binding protein 2,mPABII

Target products collectionGo to PABPN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12519-Ag-1/ GM-Tg-hg-IP12519-Ag-2 Human PABPN1 protein Human
GM-Tg-rg-IP12519-Ag-1/ GM-Tg-rg-IP12519-Ag-2 Rat PABPN1 protein Rat
GM-Tg-mg-IP12519-Ag-1/ GM-Tg-mg-IP12519-Ag-2 Mouse PABPN1 protein Mouse
GM-Tg-cynog-IP12519-Ag-1/ GM-Tg-cynog-IP12519-Ag-2 Cynomolgus/Rhesus macaque PABPN1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12519-Ag-1/ GM-Tg-felg-IP12519-Ag-2 Feline PABPN1 protein Feline
GM-Tg-cang-IP12519-Ag-1/ GM-Tg-cang-IP12519-Ag-2 Canine PABPN1 protein Canine
GM-Tg-bovg-IP12519-Ag-1/ GM-Tg-bovg-IP12519-Ag-2 Bovine PABPN1 protein Bovine
GM-Tg-equg-IP12519-Ag-1/ GM-Tg-equg-IP12519-Ag-2 Equine PABPN1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12519-Ag-1/ GM-Tg-hg-IP12519-Ag-2; GM-Tg-rg-IP12519-Ag-1/ GM-Tg-rg-IP12519-Ag-2;
GM-Tg-mg-IP12519-Ag-1/ GM-Tg-mg-IP12519-Ag-2; GM-Tg-cynog-IP12519-Ag-1/ GM-Tg-cynog-IP12519-Ag-2;
GM-Tg-felg-IP12519-Ag-1/ GM-Tg-felg-IP12519-Ag-2; GM-Tg-cang-IP12519-Ag-1/ GM-Tg-cang-IP12519-Ag-2;
GM-Tg-bovg-IP12519-Ag-1/ GM-Tg-bovg-IP12519-Ag-2; GM-Tg-equg-IP12519-Ag-1/ GM-Tg-equg-IP12519-Ag-2
Products Name PABPN1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PABPN1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PABPN1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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