Recombinant multi-species NDRG4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDRG4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.[provided by RefSeq, Jun 2011]
The Alternative Names of target: NDRG4,Protein NDRG4,Brain development-related molecule 1, N-myc downstream-regulated gene 4 protein, Vascular smooth muscle cell-associated protein 8 (SMAP-8),BDM1,SMAP8,SMAP-8

Target products collectionGo to NDRG4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1247-Ab-1/ GM-Tg-hg-IP1247-Ab-2 Human NDRG4 protein Human
GM-Tg-rg-IP1247-Ab-1/ GM-Tg-rg-IP1247-Ab-2 Rat NDRG4 protein Rat
GM-Tg-mg-IP1247-Ab-1/ GM-Tg-mg-IP1247-Ab-2 Mouse NDRG4 protein Mouse
GM-Tg-cynog-IP1247-Ab-1/ GM-Tg-cynog-IP1247-Ab-2 Cynomolgus/Rhesus macaque NDRG4 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1247-Ab-1/ GM-Tg-felg-IP1247-Ab-2 Feline NDRG4 protein Feline
GM-Tg-cang-IP1247-Ab-1/ GM-Tg-cang-IP1247-Ab-2 Canine NDRG4 protein Canine
GM-Tg-bovg-IP1247-Ab-1/ GM-Tg-bovg-IP1247-Ab-2 Bovine NDRG4 protein Bovine
GM-Tg-equg-IP1247-Ab-1/ GM-Tg-equg-IP1247-Ab-2 Equine NDRG4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1247-Ab-1/ GM-Tg-hg-IP1247-Ab-2; GM-Tg-rg-IP1247-Ab-1/ GM-Tg-rg-IP1247-Ab-2;
GM-Tg-mg-IP1247-Ab-1/ GM-Tg-mg-IP1247-Ab-2; GM-Tg-cynog-IP1247-Ab-1/ GM-Tg-cynog-IP1247-Ab-2;
GM-Tg-felg-IP1247-Ab-1/ GM-Tg-felg-IP1247-Ab-2; GM-Tg-cang-IP1247-Ab-1/ GM-Tg-cang-IP1247-Ab-2;
GM-Tg-bovg-IP1247-Ab-1/ GM-Tg-bovg-IP1247-Ab-2; GM-Tg-equg-IP1247-Ab-1/ GM-Tg-equg-IP1247-Ab-2
Products Name NDRG4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NDRG4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDRG4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.