Recombinant multi-species PUS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PUS1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]
The Alternative Names of target: A730013B20Rik,MLASA1,MPUS1,PUS1,Pseudouridylate synthase 1 homolog,Pus1,mPus1p,tRNA pseudouridine synthase 1,tRNA pseudouridine(38-40) synthase,tRNA pseudouridylate synthase I,tRNA-uridine isomerase I

Target products collectionGo to PUS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12469-Ag-1/ GM-Tg-hg-IP12469-Ag-2 Human PUS1 protein Human
GM-Tg-rg-IP12469-Ag-1/ GM-Tg-rg-IP12469-Ag-2 Rat PUS1 protein Rat
GM-Tg-mg-IP12469-Ag-1/ GM-Tg-mg-IP12469-Ag-2 Mouse PUS1 protein Mouse
GM-Tg-cynog-IP12469-Ag-1/ GM-Tg-cynog-IP12469-Ag-2 Cynomolgus/Rhesus macaque PUS1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12469-Ag-1/ GM-Tg-felg-IP12469-Ag-2 Feline PUS1 protein Feline
GM-Tg-cang-IP12469-Ag-1/ GM-Tg-cang-IP12469-Ag-2 Canine PUS1 protein Canine
GM-Tg-bovg-IP12469-Ag-1/ GM-Tg-bovg-IP12469-Ag-2 Bovine PUS1 protein Bovine
GM-Tg-equg-IP12469-Ag-1/ GM-Tg-equg-IP12469-Ag-2 Equine PUS1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12469-Ag-1/ GM-Tg-hg-IP12469-Ag-2; GM-Tg-rg-IP12469-Ag-1/ GM-Tg-rg-IP12469-Ag-2;
GM-Tg-mg-IP12469-Ag-1/ GM-Tg-mg-IP12469-Ag-2; GM-Tg-cynog-IP12469-Ag-1/ GM-Tg-cynog-IP12469-Ag-2;
GM-Tg-felg-IP12469-Ag-1/ GM-Tg-felg-IP12469-Ag-2; GM-Tg-cang-IP12469-Ag-1/ GM-Tg-cang-IP12469-Ag-2;
GM-Tg-bovg-IP12469-Ag-1/ GM-Tg-bovg-IP12469-Ag-2; GM-Tg-equg-IP12469-Ag-1/ GM-Tg-equg-IP12469-Ag-2
Products Name PUS1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PUS1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PUS1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.