Recombinant multi-species NUP214 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NUP214 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
The Alternative Names of target: 214 kDa nucleoporin,CAIN,CAN,D2H9S46E,IIAE9,NUP214,Nuclear pore complex protein Nup214,Nucleoporin Nup214,Nup214,Protein CAN,RGD1304977

Target products collectionGo to NUP214 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12427-Ag-1/ GM-Tg-hg-IP12427-Ag-2 Human NUP214 protein Human
GM-Tg-rg-IP12427-Ag-1/ GM-Tg-rg-IP12427-Ag-2 Rat NUP214 protein Rat
GM-Tg-mg-IP12427-Ag-1/ GM-Tg-mg-IP12427-Ag-2 Mouse NUP214 protein Mouse
GM-Tg-cynog-IP12427-Ag-1/ GM-Tg-cynog-IP12427-Ag-2 Cynomolgus/Rhesus macaque NUP214 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12427-Ag-1/ GM-Tg-felg-IP12427-Ag-2 Feline NUP214 protein Feline
GM-Tg-cang-IP12427-Ag-1/ GM-Tg-cang-IP12427-Ag-2 Canine NUP214 protein Canine
GM-Tg-bovg-IP12427-Ag-1/ GM-Tg-bovg-IP12427-Ag-2 Bovine NUP214 protein Bovine
GM-Tg-equg-IP12427-Ag-1/ GM-Tg-equg-IP12427-Ag-2 Equine NUP214 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12427-Ag-1/ GM-Tg-hg-IP12427-Ag-2; GM-Tg-rg-IP12427-Ag-1/ GM-Tg-rg-IP12427-Ag-2;
GM-Tg-mg-IP12427-Ag-1/ GM-Tg-mg-IP12427-Ag-2; GM-Tg-cynog-IP12427-Ag-1/ GM-Tg-cynog-IP12427-Ag-2;
GM-Tg-felg-IP12427-Ag-1/ GM-Tg-felg-IP12427-Ag-2; GM-Tg-cang-IP12427-Ag-1/ GM-Tg-cang-IP12427-Ag-2;
GM-Tg-bovg-IP12427-Ag-1/ GM-Tg-bovg-IP12427-Ag-2; GM-Tg-equg-IP12427-Ag-1/ GM-Tg-equg-IP12427-Ag-2
Products Name NUP214 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NUP214
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NUP214 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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