Recombinant multi-species NCKIPSD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NCKIPSD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019]
The Alternative Names of target: 54 kDa VacA-interacting protein,54 kDa vimentin-interacting protein (VIP54),90 kDa SH3 protein interacting with Nck,AF3P21,AF3p21,DIP,DIP1,Dia-interacting protein 1 (DIP-1),Diaphanous protein-interacting protein,NCK-interacting protein with SH3 domain,NCKIPSD,Nckipsd,ORF1,SH3 adapter protein SPIN90,SPIN90,VIP54,WASLBP,WASP-interacting SH3-domain protein (WISH),WISH,Wasbp,Wiskott-Aldrich syndrome protein-interacting protein
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP1241-Ag-1/ GM-Tg-hg-IP1241-Ag-2 | Human NCKIPSD protein | Human |
GM-Tg-rg-IP1241-Ag-1/ GM-Tg-rg-IP1241-Ag-2 | Rat NCKIPSD protein | Rat |
GM-Tg-mg-IP1241-Ag-1/ GM-Tg-mg-IP1241-Ag-2 | Mouse NCKIPSD protein | Mouse |
GM-Tg-cynog-IP1241-Ag-1/ GM-Tg-cynog-IP1241-Ag-2 | Cynomolgus/Rhesus macaque NCKIPSD protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP1241-Ag-1/ GM-Tg-felg-IP1241-Ag-2 | Feline NCKIPSD protein | Feline |
GM-Tg-cang-IP1241-Ag-1/ GM-Tg-cang-IP1241-Ag-2 | Canine NCKIPSD protein | Canine |
GM-Tg-bovg-IP1241-Ag-1/ GM-Tg-bovg-IP1241-Ag-2 | Bovine NCKIPSD protein | Bovine |
GM-Tg-equg-IP1241-Ag-1/ GM-Tg-equg-IP1241-Ag-2 | Equine NCKIPSD protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-IP1241-Ag-1/ GM-Tg-hg-IP1241-Ag-2;
GM-Tg-rg-IP1241-Ag-1/ GM-Tg-rg-IP1241-Ag-2;
GM-Tg-mg-IP1241-Ag-1/ GM-Tg-mg-IP1241-Ag-2; GM-Tg-cynog-IP1241-Ag-1/ GM-Tg-cynog-IP1241-Ag-2; GM-Tg-felg-IP1241-Ag-1/ GM-Tg-felg-IP1241-Ag-2; GM-Tg-cang-IP1241-Ag-1/ GM-Tg-cang-IP1241-Ag-2; GM-Tg-bovg-IP1241-Ag-1/ GM-Tg-bovg-IP1241-Ag-2; GM-Tg-equg-IP1241-Ag-1/ GM-Tg-equg-IP1241-Ag-2 |
Products Name | NCKIPSD protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | NCKIPSD |
Protein Sub-location | Introcelluar Protein |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NCKIPSD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.