Recombinant multi-species KAT6A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KAT6A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
The Alternative Names of target: 1500036M03,9930021N24Rik,ARTHS,Histone acetyltransferase KAT6A,KAT6A,Kat6a,MOZ,MRD32,MYST-3,MYST3,Monocytic leukemia zinc finger protein,Moz,Myst3,RUNXBP2,Runt-related transcription factor-binding protein 2,Runxbp2,SAS2 and TIP60 protein 3 (MYST-3),YBF2/SAS3,ZC2HC6A,ZNF220,Zfp220,Zinc finger protein 220,Znf220

Target products collectionGo to KAT6A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12357-Ag-1/ GM-Tg-hg-IP12357-Ag-2 Human KAT6A protein Human
GM-Tg-rg-IP12357-Ag-1/ GM-Tg-rg-IP12357-Ag-2 Rat KAT6A protein Rat
GM-Tg-mg-IP12357-Ag-1/ GM-Tg-mg-IP12357-Ag-2 Mouse KAT6A protein Mouse
GM-Tg-cynog-IP12357-Ag-1/ GM-Tg-cynog-IP12357-Ag-2 Cynomolgus/Rhesus macaque KAT6A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12357-Ag-1/ GM-Tg-felg-IP12357-Ag-2 Feline KAT6A protein Feline
GM-Tg-cang-IP12357-Ag-1/ GM-Tg-cang-IP12357-Ag-2 Canine KAT6A protein Canine
GM-Tg-bovg-IP12357-Ag-1/ GM-Tg-bovg-IP12357-Ag-2 Bovine KAT6A protein Bovine
GM-Tg-equg-IP12357-Ag-1/ GM-Tg-equg-IP12357-Ag-2 Equine KAT6A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12357-Ag-1/ GM-Tg-hg-IP12357-Ag-2; GM-Tg-rg-IP12357-Ag-1/ GM-Tg-rg-IP12357-Ag-2;
GM-Tg-mg-IP12357-Ag-1/ GM-Tg-mg-IP12357-Ag-2; GM-Tg-cynog-IP12357-Ag-1/ GM-Tg-cynog-IP12357-Ag-2;
GM-Tg-felg-IP12357-Ag-1/ GM-Tg-felg-IP12357-Ag-2; GM-Tg-cang-IP12357-Ag-1/ GM-Tg-cang-IP12357-Ag-2;
GM-Tg-bovg-IP12357-Ag-1/ GM-Tg-bovg-IP12357-Ag-2; GM-Tg-equg-IP12357-Ag-1/ GM-Tg-equg-IP12357-Ag-2
Products Name KAT6A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KAT6A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KAT6A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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