Recombinant multi-species MYRF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYRF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
The Alternative Names of target: 11orf9,6030439E18,C11orf9,C14H11orf9,C18H11orf9,C29H11orf9,CD1H11orf9,CUGS,Gm1804,Gm98,MMERV,MRF,MYRF,Mrf,Myelin gene regulatory factor,Myelin regulatory factor,Myrf,Ndt80,RGD1306622,pqn-47

Target products collectionGo to MYRF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1229-Ag-1/ GM-Tg-hg-IP1229-Ag-2 Human MYRF protein Human
GM-Tg-rg-IP1229-Ag-1/ GM-Tg-rg-IP1229-Ag-2 Rat MYRF protein Rat
GM-Tg-mg-IP1229-Ag-1/ GM-Tg-mg-IP1229-Ag-2 Mouse MYRF protein Mouse
GM-Tg-cynog-IP1229-Ag-1/ GM-Tg-cynog-IP1229-Ag-2 Cynomolgus/Rhesus macaque MYRF protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1229-Ag-1/ GM-Tg-felg-IP1229-Ag-2 Feline MYRF protein Feline
GM-Tg-cang-IP1229-Ag-1/ GM-Tg-cang-IP1229-Ag-2 Canine MYRF protein Canine
GM-Tg-bovg-IP1229-Ag-1/ GM-Tg-bovg-IP1229-Ag-2 Bovine MYRF protein Bovine
GM-Tg-equg-IP1229-Ag-1/ GM-Tg-equg-IP1229-Ag-2 Equine MYRF protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1229-Ag-1/ GM-Tg-hg-IP1229-Ag-2; GM-Tg-rg-IP1229-Ag-1/ GM-Tg-rg-IP1229-Ag-2;
GM-Tg-mg-IP1229-Ag-1/ GM-Tg-mg-IP1229-Ag-2; GM-Tg-cynog-IP1229-Ag-1/ GM-Tg-cynog-IP1229-Ag-2;
GM-Tg-felg-IP1229-Ag-1/ GM-Tg-felg-IP1229-Ag-2; GM-Tg-cang-IP1229-Ag-1/ GM-Tg-cang-IP1229-Ag-2;
GM-Tg-bovg-IP1229-Ag-1/ GM-Tg-bovg-IP1229-Ag-2; GM-Tg-equg-IP1229-Ag-1/ GM-Tg-equg-IP1229-Ag-2
Products Name MYRF protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MYRF
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYRF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.