Recombinant multi-species BAT1/DDX39B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAT1/DDX39B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene. [provided by RefSeq, Feb 2011]
The Alternative Names of target: 0610030D10Rik,56 kDa U2AF65-associated protein,ATP-dependent RNA helicase p47,BAT1,Bat-1,Bat1,Bat1a,D17H6S81E,D17H6S81E-1,D6S81E,D6S81Eh,DDX39B,DEAD box protein UAP56,Ddx39b,HLA-B-associated transcript 1 protein,Spliceosome RNA helicase DDX39B,UAP56,p47
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP12139-Ag-1/ GM-Tg-hg-IP12139-Ag-2 | Human BAT1/DDX39B protein | Human |
| GM-Tg-rg-IP12139-Ag-1/ GM-Tg-rg-IP12139-Ag-2 | Rat BAT1/DDX39B protein | Rat |
| GM-Tg-mg-IP12139-Ag-1/ GM-Tg-mg-IP12139-Ag-2 | Mouse BAT1/DDX39B protein | Mouse |
| GM-Tg-cynog-IP12139-Ag-1/ GM-Tg-cynog-IP12139-Ag-2 | Cynomolgus/Rhesus macaque BAT1/DDX39B protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP12139-Ag-1/ GM-Tg-felg-IP12139-Ag-2 | Feline BAT1/DDX39B protein | Feline |
| GM-Tg-cang-IP12139-Ag-1/ GM-Tg-cang-IP12139-Ag-2 | Canine BAT1/DDX39B protein | Canine |
| GM-Tg-bovg-IP12139-Ag-1/ GM-Tg-bovg-IP12139-Ag-2 | Bovine BAT1/DDX39B protein | Bovine |
| GM-Tg-equg-IP12139-Ag-1/ GM-Tg-equg-IP12139-Ag-2 | Equine BAT1/DDX39B protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP12139-Ag-1/ GM-Tg-hg-IP12139-Ag-2;
GM-Tg-rg-IP12139-Ag-1/ GM-Tg-rg-IP12139-Ag-2;
GM-Tg-mg-IP12139-Ag-1/ GM-Tg-mg-IP12139-Ag-2; GM-Tg-cynog-IP12139-Ag-1/ GM-Tg-cynog-IP12139-Ag-2; GM-Tg-felg-IP12139-Ag-1/ GM-Tg-felg-IP12139-Ag-2; GM-Tg-cang-IP12139-Ag-1/ GM-Tg-cang-IP12139-Ag-2; GM-Tg-bovg-IP12139-Ag-1/ GM-Tg-bovg-IP12139-Ag-2; GM-Tg-equg-IP12139-Ag-1/ GM-Tg-equg-IP12139-Ag-2 |
| Products Name | BAT1/DDX39B protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | BAT1/DDX39B |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAT1/DDX39B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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entities. Leveraging the sophisticated
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characterized by high binding affinity,
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
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myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.