Recombinant multi-species WDR77 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WDR77 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
The Alternative Names of target: 2610003I18Rik,2610312E17Rik,Ac2-269,Androgen receptor cofactor p44,HKMT1069,MEP-50,MEP50,Methylosome protein 50 (MEP-50),Methylosome protein WDR77,Nbla10071,RGD1310479,WD repeat-containing protein 77,WDR77,Wdr77,p44,p44/MEP50,p44/Mep50
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP12107-Ag-1/ GM-Tg-hg-IP12107-Ag-2 | Human WDR77 protein | Human |
| GM-Tg-rg-IP12107-Ag-1/ GM-Tg-rg-IP12107-Ag-2 | Rat WDR77 protein | Rat |
| GM-Tg-mg-IP12107-Ag-1/ GM-Tg-mg-IP12107-Ag-2 | Mouse WDR77 protein | Mouse |
| GM-Tg-cynog-IP12107-Ag-1/ GM-Tg-cynog-IP12107-Ag-2 | Cynomolgus/Rhesus macaque WDR77 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP12107-Ag-1/ GM-Tg-felg-IP12107-Ag-2 | Feline WDR77 protein | Feline |
| GM-Tg-cang-IP12107-Ag-1/ GM-Tg-cang-IP12107-Ag-2 | Canine WDR77 protein | Canine |
| GM-Tg-bovg-IP12107-Ag-1/ GM-Tg-bovg-IP12107-Ag-2 | Bovine WDR77 protein | Bovine |
| GM-Tg-equg-IP12107-Ag-1/ GM-Tg-equg-IP12107-Ag-2 | Equine WDR77 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP12107-Ag-1/ GM-Tg-hg-IP12107-Ag-2;
GM-Tg-rg-IP12107-Ag-1/ GM-Tg-rg-IP12107-Ag-2;
GM-Tg-mg-IP12107-Ag-1/ GM-Tg-mg-IP12107-Ag-2; GM-Tg-cynog-IP12107-Ag-1/ GM-Tg-cynog-IP12107-Ag-2; GM-Tg-felg-IP12107-Ag-1/ GM-Tg-felg-IP12107-Ag-2; GM-Tg-cang-IP12107-Ag-1/ GM-Tg-cang-IP12107-Ag-2; GM-Tg-bovg-IP12107-Ag-1/ GM-Tg-bovg-IP12107-Ag-2; GM-Tg-equg-IP12107-Ag-1/ GM-Tg-equg-IP12107-Ag-2 |
| Products Name | WDR77 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | WDR77 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WDR77 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.