Recombinant multi-species WDR77 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WDR77 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
The Alternative Names of target: 2610003I18Rik,2610312E17Rik,Ac2-269,Androgen receptor cofactor p44,HKMT1069,MEP-50,MEP50,Methylosome protein 50 (MEP-50),Methylosome protein WDR77,Nbla10071,RGD1310479,WD repeat-containing protein 77,WDR77,Wdr77,p44,p44/MEP50,p44/Mep50

Target products collectionGo to WDR77 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12107-Ag-1/ GM-Tg-hg-IP12107-Ag-2 Human WDR77 protein Human
GM-Tg-rg-IP12107-Ag-1/ GM-Tg-rg-IP12107-Ag-2 Rat WDR77 protein Rat
GM-Tg-mg-IP12107-Ag-1/ GM-Tg-mg-IP12107-Ag-2 Mouse WDR77 protein Mouse
GM-Tg-cynog-IP12107-Ag-1/ GM-Tg-cynog-IP12107-Ag-2 Cynomolgus/Rhesus macaque WDR77 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12107-Ag-1/ GM-Tg-felg-IP12107-Ag-2 Feline WDR77 protein Feline
GM-Tg-cang-IP12107-Ag-1/ GM-Tg-cang-IP12107-Ag-2 Canine WDR77 protein Canine
GM-Tg-bovg-IP12107-Ag-1/ GM-Tg-bovg-IP12107-Ag-2 Bovine WDR77 protein Bovine
GM-Tg-equg-IP12107-Ag-1/ GM-Tg-equg-IP12107-Ag-2 Equine WDR77 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12107-Ag-1/ GM-Tg-hg-IP12107-Ag-2; GM-Tg-rg-IP12107-Ag-1/ GM-Tg-rg-IP12107-Ag-2;
GM-Tg-mg-IP12107-Ag-1/ GM-Tg-mg-IP12107-Ag-2; GM-Tg-cynog-IP12107-Ag-1/ GM-Tg-cynog-IP12107-Ag-2;
GM-Tg-felg-IP12107-Ag-1/ GM-Tg-felg-IP12107-Ag-2; GM-Tg-cang-IP12107-Ag-1/ GM-Tg-cang-IP12107-Ag-2;
GM-Tg-bovg-IP12107-Ag-1/ GM-Tg-bovg-IP12107-Ag-2; GM-Tg-equg-IP12107-Ag-1/ GM-Tg-equg-IP12107-Ag-2
Products Name WDR77 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name WDR77
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WDR77 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.