Recombinant multi-species FTO protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FTO protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
The Alternative Names of target: ALKBH9,Alpha-ketoglutarate-dependent dioxygenase FTO,BMIQ14,FTO,Fat mass and obesity-associated protein,Fto,GDFD,IFEX9,RGD1305121,U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO,U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO,mKIAA1752,mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (m6A(m)-demethylase FTO),mRNA N(6)-methyladenosine demethylase FTO,tRNA N1-methyl adenine demethylase FTO

Target products collectionGo to FTO products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP12099-Ag-1/ GM-Tg-hg-IP12099-Ag-2 Human FTO protein Human
GM-Tg-rg-IP12099-Ag-1/ GM-Tg-rg-IP12099-Ag-2 Rat FTO protein Rat
GM-Tg-mg-IP12099-Ag-1/ GM-Tg-mg-IP12099-Ag-2 Mouse FTO protein Mouse
GM-Tg-cynog-IP12099-Ag-1/ GM-Tg-cynog-IP12099-Ag-2 Cynomolgus/Rhesus macaque FTO protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP12099-Ag-1/ GM-Tg-felg-IP12099-Ag-2 Feline FTO protein Feline
GM-Tg-cang-IP12099-Ag-1/ GM-Tg-cang-IP12099-Ag-2 Canine FTO protein Canine
GM-Tg-bovg-IP12099-Ag-1/ GM-Tg-bovg-IP12099-Ag-2 Bovine FTO protein Bovine
GM-Tg-equg-IP12099-Ag-1/ GM-Tg-equg-IP12099-Ag-2 Equine FTO protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP12099-Ag-1/ GM-Tg-hg-IP12099-Ag-2; GM-Tg-rg-IP12099-Ag-1/ GM-Tg-rg-IP12099-Ag-2;
GM-Tg-mg-IP12099-Ag-1/ GM-Tg-mg-IP12099-Ag-2; GM-Tg-cynog-IP12099-Ag-1/ GM-Tg-cynog-IP12099-Ag-2;
GM-Tg-felg-IP12099-Ag-1/ GM-Tg-felg-IP12099-Ag-2; GM-Tg-cang-IP12099-Ag-1/ GM-Tg-cang-IP12099-Ag-2;
GM-Tg-bovg-IP12099-Ag-1/ GM-Tg-bovg-IP12099-Ag-2; GM-Tg-equg-IP12099-Ag-1/ GM-Tg-equg-IP12099-Ag-2
Products Name FTO protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FTO
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FTO protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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