Recombinant multi-species PRR14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRR14 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene tethers heterochromatin to the nuclear laminar scaffold by binding heterochromatin protein 1 (HP1) and the nuclear lamina. The tether is broken during mitosis and reforms quickly after mitosis, with the encoded protein first binding HP1 and then attaching to the nuclear lamina. This protein also has been shown to promote MyoD activity and skeletal myogenesis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2016]
The Alternative Names of target: AABR07005779.1,MECP2_e1,Mecp2,PRR14,Proline-rich protein 14,Prr14
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP12068-Ag-1/ GM-Tg-hg-IP12068-Ag-2 | Human PRR14 protein | Human |
| GM-Tg-rg-IP12068-Ag-1/ GM-Tg-rg-IP12068-Ag-2 | Rat PRR14 protein | Rat |
| GM-Tg-mg-IP12068-Ag-1/ GM-Tg-mg-IP12068-Ag-2 | Mouse PRR14 protein | Mouse |
| GM-Tg-cynog-IP12068-Ag-1/ GM-Tg-cynog-IP12068-Ag-2 | Cynomolgus/Rhesus macaque PRR14 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP12068-Ag-1/ GM-Tg-felg-IP12068-Ag-2 | Feline PRR14 protein | Feline |
| GM-Tg-cang-IP12068-Ag-1/ GM-Tg-cang-IP12068-Ag-2 | Canine PRR14 protein | Canine |
| GM-Tg-bovg-IP12068-Ag-1/ GM-Tg-bovg-IP12068-Ag-2 | Bovine PRR14 protein | Bovine |
| GM-Tg-equg-IP12068-Ag-1/ GM-Tg-equg-IP12068-Ag-2 | Equine PRR14 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP12068-Ag-1/ GM-Tg-hg-IP12068-Ag-2;
GM-Tg-rg-IP12068-Ag-1/ GM-Tg-rg-IP12068-Ag-2;
GM-Tg-mg-IP12068-Ag-1/ GM-Tg-mg-IP12068-Ag-2; GM-Tg-cynog-IP12068-Ag-1/ GM-Tg-cynog-IP12068-Ag-2; GM-Tg-felg-IP12068-Ag-1/ GM-Tg-felg-IP12068-Ag-2; GM-Tg-cang-IP12068-Ag-1/ GM-Tg-cang-IP12068-Ag-2; GM-Tg-bovg-IP12068-Ag-1/ GM-Tg-bovg-IP12068-Ag-2; GM-Tg-equg-IP12068-Ag-1/ GM-Tg-equg-IP12068-Ag-2 |
| Products Name | PRR14 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PRR14 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRR14 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.