Recombinant multi-species YWHAZ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YWHAZ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]
The Alternative Names of target: 1110013I11Rik,14-3-3 protein zeta/delta,14-3-3-zeta,14-3-3z,14-3-3zeta,HEL-S-3,HEL-S-93,HEL4,KCIP-1,POPCHAS,Protein kinase C inhibitor protein 1 (KCIP-1),YWHAD,YWHAZ,Ywhaz

Target products collectionGo to YWHAZ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11941-Ag-1/ GM-Tg-hg-IP11941-Ag-2 Human YWHAZ protein Human
GM-Tg-rg-IP11941-Ag-1/ GM-Tg-rg-IP11941-Ag-2 Rat YWHAZ protein Rat
GM-Tg-mg-IP11941-Ag-1/ GM-Tg-mg-IP11941-Ag-2 Mouse YWHAZ protein Mouse
GM-Tg-cynog-IP11941-Ag-1/ GM-Tg-cynog-IP11941-Ag-2 Cynomolgus/Rhesus macaque YWHAZ protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11941-Ag-1/ GM-Tg-felg-IP11941-Ag-2 Feline YWHAZ protein Feline
GM-Tg-cang-IP11941-Ag-1/ GM-Tg-cang-IP11941-Ag-2 Canine YWHAZ protein Canine
GM-Tg-bovg-IP11941-Ag-1/ GM-Tg-bovg-IP11941-Ag-2 Bovine YWHAZ protein Bovine
GM-Tg-equg-IP11941-Ag-1/ GM-Tg-equg-IP11941-Ag-2 Equine YWHAZ protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11941-Ag-1/ GM-Tg-hg-IP11941-Ag-2; GM-Tg-rg-IP11941-Ag-1/ GM-Tg-rg-IP11941-Ag-2;
GM-Tg-mg-IP11941-Ag-1/ GM-Tg-mg-IP11941-Ag-2; GM-Tg-cynog-IP11941-Ag-1/ GM-Tg-cynog-IP11941-Ag-2;
GM-Tg-felg-IP11941-Ag-1/ GM-Tg-felg-IP11941-Ag-2; GM-Tg-cang-IP11941-Ag-1/ GM-Tg-cang-IP11941-Ag-2;
GM-Tg-bovg-IP11941-Ag-1/ GM-Tg-bovg-IP11941-Ag-2; GM-Tg-equg-IP11941-Ag-1/ GM-Tg-equg-IP11941-Ag-2
Products Name YWHAZ protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name YWHAZ
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YWHAZ protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.