Recombinant multi-species YWHAB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YWHAB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1300003C17Rik,14-3-3 protein beta/alpha,14-3-3b,GW128,HEL-S-1,HS1,KCIP-1,Protein 1054,Protein kinase C inhibitor protein 1 (KCIP-1),YWHAA,YWHAB,Ywhab

Target products collectionGo to YWHAB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11938-Ag-1/ GM-Tg-hg-IP11938-Ag-2 Human YWHAB protein Human
GM-Tg-rg-IP11938-Ag-1/ GM-Tg-rg-IP11938-Ag-2 Rat YWHAB protein Rat
GM-Tg-mg-IP11938-Ag-1/ GM-Tg-mg-IP11938-Ag-2 Mouse YWHAB protein Mouse
GM-Tg-cynog-IP11938-Ag-1/ GM-Tg-cynog-IP11938-Ag-2 Cynomolgus/Rhesus macaque YWHAB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11938-Ag-1/ GM-Tg-felg-IP11938-Ag-2 Feline YWHAB protein Feline
GM-Tg-cang-IP11938-Ag-1/ GM-Tg-cang-IP11938-Ag-2 Canine YWHAB protein Canine
GM-Tg-bovg-IP11938-Ag-1/ GM-Tg-bovg-IP11938-Ag-2 Bovine YWHAB protein Bovine
GM-Tg-equg-IP11938-Ag-1/ GM-Tg-equg-IP11938-Ag-2 Equine YWHAB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11938-Ag-1/ GM-Tg-hg-IP11938-Ag-2; GM-Tg-rg-IP11938-Ag-1/ GM-Tg-rg-IP11938-Ag-2;
GM-Tg-mg-IP11938-Ag-1/ GM-Tg-mg-IP11938-Ag-2; GM-Tg-cynog-IP11938-Ag-1/ GM-Tg-cynog-IP11938-Ag-2;
GM-Tg-felg-IP11938-Ag-1/ GM-Tg-felg-IP11938-Ag-2; GM-Tg-cang-IP11938-Ag-1/ GM-Tg-cang-IP11938-Ag-2;
GM-Tg-bovg-IP11938-Ag-1/ GM-Tg-bovg-IP11938-Ag-2; GM-Tg-equg-IP11938-Ag-1/ GM-Tg-equg-IP11938-Ag-2
Products Name YWHAB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name YWHAB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine YWHAB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.