Recombinant multi-species WHSC1/NSD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WHSC1/NSD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5830445G22Rik,9430010A17Rik,C130020C13Rik,D030027O06Rik,D930023B08Rik,Histone-lysine N-methyltransferase NSD2,KMT3F,KMT3G,MMSET,Multiple myeloma SET domain-containing protein (MMSET),NSD2,Nsd2,Nuclear SET domain-containing protein 2,Protein trithorax-5,RAUST,REIIBP,RGD1565590,TRX5,WHS,WHSC1,Whsc1,Whsc1l,Wolf-Hirschhorn syndrome candidate 1 protein,mKIAA1090

Target products collectionGo to WHSC1/NSD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11928-Ag-1/ GM-Tg-hg-IP11928-Ag-2 Human WHSC1/NSD2 protein Human
GM-Tg-rg-IP11928-Ag-1/ GM-Tg-rg-IP11928-Ag-2 Rat WHSC1/NSD2 protein Rat
GM-Tg-mg-IP11928-Ag-1/ GM-Tg-mg-IP11928-Ag-2 Mouse WHSC1/NSD2 protein Mouse
GM-Tg-cynog-IP11928-Ag-1/ GM-Tg-cynog-IP11928-Ag-2 Cynomolgus/Rhesus macaque WHSC1/NSD2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11928-Ag-1/ GM-Tg-felg-IP11928-Ag-2 Feline WHSC1/NSD2 protein Feline
GM-Tg-cang-IP11928-Ag-1/ GM-Tg-cang-IP11928-Ag-2 Canine WHSC1/NSD2 protein Canine
GM-Tg-bovg-IP11928-Ag-1/ GM-Tg-bovg-IP11928-Ag-2 Bovine WHSC1/NSD2 protein Bovine
GM-Tg-equg-IP11928-Ag-1/ GM-Tg-equg-IP11928-Ag-2 Equine WHSC1/NSD2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11928-Ag-1/ GM-Tg-hg-IP11928-Ag-2; GM-Tg-rg-IP11928-Ag-1/ GM-Tg-rg-IP11928-Ag-2;
GM-Tg-mg-IP11928-Ag-1/ GM-Tg-mg-IP11928-Ag-2; GM-Tg-cynog-IP11928-Ag-1/ GM-Tg-cynog-IP11928-Ag-2;
GM-Tg-felg-IP11928-Ag-1/ GM-Tg-felg-IP11928-Ag-2; GM-Tg-cang-IP11928-Ag-1/ GM-Tg-cang-IP11928-Ag-2;
GM-Tg-bovg-IP11928-Ag-1/ GM-Tg-bovg-IP11928-Ag-2; GM-Tg-equg-IP11928-Ag-1/ GM-Tg-equg-IP11928-Ag-2
Products Name WHSC1/NSD2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name WHSC1/NSD2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine WHSC1/NSD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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