Recombinant multi-species Vinculin/VCL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Vinculin/VCL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 9430097D22,CMD1W,CMH15,HEL114,MV,MVCL,Metavinculin (MV),VCL,VINC,Vcl,Vinculin

Target products collectionGo to Vinculin/VCL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11922-Ag-1/ GM-Tg-hg-IP11922-Ag-2 Human Vinculin/VCL protein Human
GM-Tg-rg-IP11922-Ag-1/ GM-Tg-rg-IP11922-Ag-2 Rat Vinculin/VCL protein Rat
GM-Tg-mg-IP11922-Ag-1/ GM-Tg-mg-IP11922-Ag-2 Mouse Vinculin/VCL protein Mouse
GM-Tg-cynog-IP11922-Ag-1/ GM-Tg-cynog-IP11922-Ag-2 Cynomolgus/Rhesus macaque Vinculin/VCL protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11922-Ag-1/ GM-Tg-felg-IP11922-Ag-2 Feline Vinculin/VCL protein Feline
GM-Tg-cang-IP11922-Ag-1/ GM-Tg-cang-IP11922-Ag-2 Canine Vinculin/VCL protein Canine
GM-Tg-bovg-IP11922-Ag-1/ GM-Tg-bovg-IP11922-Ag-2 Bovine Vinculin/VCL protein Bovine
GM-Tg-equg-IP11922-Ag-1/ GM-Tg-equg-IP11922-Ag-2 Equine Vinculin/VCL protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11922-Ag-1/ GM-Tg-hg-IP11922-Ag-2; GM-Tg-rg-IP11922-Ag-1/ GM-Tg-rg-IP11922-Ag-2;
GM-Tg-mg-IP11922-Ag-1/ GM-Tg-mg-IP11922-Ag-2; GM-Tg-cynog-IP11922-Ag-1/ GM-Tg-cynog-IP11922-Ag-2;
GM-Tg-felg-IP11922-Ag-1/ GM-Tg-felg-IP11922-Ag-2; GM-Tg-cang-IP11922-Ag-1/ GM-Tg-cang-IP11922-Ag-2;
GM-Tg-bovg-IP11922-Ag-1/ GM-Tg-bovg-IP11922-Ag-2; GM-Tg-equg-IP11922-Ag-1/ GM-Tg-equg-IP11922-Ag-2
Products Name Vinculin/VCL protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Vinculin/VCL
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Vinculin/VCL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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