Recombinant multi-species UNG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UNG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]
The Alternative Names of target: DGU,HIGM4,HIGM5,UDG,UNG,UNG1,UNG15,UNG2,Ung,Uracil-DNA glycosylase

Target products collectionGo to UNG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11906-Ag-1/ GM-Tg-hg-IP11906-Ag-2 Human UNG protein Human
GM-Tg-rg-IP11906-Ag-1/ GM-Tg-rg-IP11906-Ag-2 Rat UNG protein Rat
GM-Tg-mg-IP11906-Ag-1/ GM-Tg-mg-IP11906-Ag-2 Mouse UNG protein Mouse
GM-Tg-cynog-IP11906-Ag-1/ GM-Tg-cynog-IP11906-Ag-2 Cynomolgus/Rhesus macaque UNG protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11906-Ag-1/ GM-Tg-felg-IP11906-Ag-2 Feline UNG protein Feline
GM-Tg-cang-IP11906-Ag-1/ GM-Tg-cang-IP11906-Ag-2 Canine UNG protein Canine
GM-Tg-bovg-IP11906-Ag-1/ GM-Tg-bovg-IP11906-Ag-2 Bovine UNG protein Bovine
GM-Tg-equg-IP11906-Ag-1/ GM-Tg-equg-IP11906-Ag-2 Equine UNG protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11906-Ag-1/ GM-Tg-hg-IP11906-Ag-2; GM-Tg-rg-IP11906-Ag-1/ GM-Tg-rg-IP11906-Ag-2;
GM-Tg-mg-IP11906-Ag-1/ GM-Tg-mg-IP11906-Ag-2; GM-Tg-cynog-IP11906-Ag-1/ GM-Tg-cynog-IP11906-Ag-2;
GM-Tg-felg-IP11906-Ag-1/ GM-Tg-felg-IP11906-Ag-2; GM-Tg-cang-IP11906-Ag-1/ GM-Tg-cang-IP11906-Ag-2;
GM-Tg-bovg-IP11906-Ag-1/ GM-Tg-bovg-IP11906-Ag-2; GM-Tg-equg-IP11906-Ag-1/ GM-Tg-equg-IP11906-Ag-2
Products Name UNG protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name UNG
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UNG protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.