Recombinant multi-species TP73 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TP73 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]
The Alternative Names of target: CILD47,P73,TAp73,TP73,Tp73,Trp73,Tumor protein p73,deltaNp73,p53-like transcription factor,p53-related protein,p73

Target products collectionGo to TP73 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11713-Ag-1/ GM-Tg-hg-IP11713-Ag-2 Human TP73 protein Human
GM-Tg-rg-IP11713-Ag-1/ GM-Tg-rg-IP11713-Ag-2 Rat TP73 protein Rat
GM-Tg-mg-IP11713-Ag-1/ GM-Tg-mg-IP11713-Ag-2 Mouse TP73 protein Mouse
GM-Tg-cynog-IP11713-Ag-1/ GM-Tg-cynog-IP11713-Ag-2 Cynomolgus/Rhesus macaque TP73 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11713-Ag-1/ GM-Tg-felg-IP11713-Ag-2 Feline TP73 protein Feline
GM-Tg-cang-IP11713-Ag-1/ GM-Tg-cang-IP11713-Ag-2 Canine TP73 protein Canine
GM-Tg-bovg-IP11713-Ag-1/ GM-Tg-bovg-IP11713-Ag-2 Bovine TP73 protein Bovine
GM-Tg-equg-IP11713-Ag-1/ GM-Tg-equg-IP11713-Ag-2 Equine TP73 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11713-Ag-1/ GM-Tg-hg-IP11713-Ag-2; GM-Tg-rg-IP11713-Ag-1/ GM-Tg-rg-IP11713-Ag-2;
GM-Tg-mg-IP11713-Ag-1/ GM-Tg-mg-IP11713-Ag-2; GM-Tg-cynog-IP11713-Ag-1/ GM-Tg-cynog-IP11713-Ag-2;
GM-Tg-felg-IP11713-Ag-1/ GM-Tg-felg-IP11713-Ag-2; GM-Tg-cang-IP11713-Ag-1/ GM-Tg-cang-IP11713-Ag-2;
GM-Tg-bovg-IP11713-Ag-1/ GM-Tg-bovg-IP11713-Ag-2; GM-Tg-equg-IP11713-Ag-1/ GM-Tg-equg-IP11713-Ag-2
Products Name TP73 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TP73
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TP73 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.