Recombinant multi-species peroxiredoxin 2/PRDX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine peroxiredoxin 2/PRDX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
The Alternative Names of target: Band-8,HEL-S-2a,NKEF-B,NKEFB,Natural killer cell-enhancing factor B (NKEF-B),NkefB,PRDX2,PRP,PRX2,PRXII,PTX1,Peroxiredoxin-2,Prdx2,PrxII,TDPX1,TDX1,TPX1,TPx,TPx-B,TR,TSA,Tdpx1,Thiol-specific antioxidant protein (TSA),Thioredoxin peroxidase 1,Thioredoxin-dependent peroxide reductase 1,Thioredoxin-dependent peroxiredoxin 2,Torin,peroxiredoxin 2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP11668-Ag-1/ GM-Tg-hg-IP11668-Ag-2 | Human peroxiredoxin 2/PRDX2 protein | Human |
| GM-Tg-rg-IP11668-Ag-1/ GM-Tg-rg-IP11668-Ag-2 | Rat peroxiredoxin 2/PRDX2 protein | Rat |
| GM-Tg-mg-IP11668-Ag-1/ GM-Tg-mg-IP11668-Ag-2 | Mouse peroxiredoxin 2/PRDX2 protein | Mouse |
| GM-Tg-cynog-IP11668-Ag-1/ GM-Tg-cynog-IP11668-Ag-2 | Cynomolgus/Rhesus macaque peroxiredoxin 2/PRDX2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP11668-Ag-1/ GM-Tg-felg-IP11668-Ag-2 | Feline peroxiredoxin 2/PRDX2 protein | Feline |
| GM-Tg-cang-IP11668-Ag-1/ GM-Tg-cang-IP11668-Ag-2 | Canine peroxiredoxin 2/PRDX2 protein | Canine |
| GM-Tg-bovg-IP11668-Ag-1/ GM-Tg-bovg-IP11668-Ag-2 | Bovine peroxiredoxin 2/PRDX2 protein | Bovine |
| GM-Tg-equg-IP11668-Ag-1/ GM-Tg-equg-IP11668-Ag-2 | Equine peroxiredoxin 2/PRDX2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-IP11668-Ag-1/ GM-Tg-hg-IP11668-Ag-2;
GM-Tg-rg-IP11668-Ag-1/ GM-Tg-rg-IP11668-Ag-2;
GM-Tg-mg-IP11668-Ag-1/ GM-Tg-mg-IP11668-Ag-2; GM-Tg-cynog-IP11668-Ag-1/ GM-Tg-cynog-IP11668-Ag-2; GM-Tg-felg-IP11668-Ag-1/ GM-Tg-felg-IP11668-Ag-2; GM-Tg-cang-IP11668-Ag-1/ GM-Tg-cang-IP11668-Ag-2; GM-Tg-bovg-IP11668-Ag-1/ GM-Tg-bovg-IP11668-Ag-2; GM-Tg-equg-IP11668-Ag-1/ GM-Tg-equg-IP11668-Ag-2 |
| Products Name | peroxiredoxin 2/PRDX2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | peroxiredoxin 2/PRDX2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine peroxiredoxin 2/PRDX2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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