Recombinant multi-species HNF1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNF1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
The Alternative Names of target: ADTKD3,FJHN,HNF-1-beta,HNF-1B,HNF-1Beta,HNF-1b,HNF1B,HNF1beta,HNF2,HPC11,Hepatocyte nuclear factor 1-beta,Hnf1b,Hnf1beta,Homeoprotein LFB3,LF-B3,LFB3,MODY5,RCAD,T2D,TCF-2,TCF2,Tcf-2,Tcf2,Transcription factor 2 (TCF-2),VHNF1,Variant hepatic nuclear factor 1 (vHNF1),vHNF1

Target products collectionGo to HNF1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11643-Ag-1/ GM-Tg-hg-IP11643-Ag-2 Human HNF1B protein Human
GM-Tg-rg-IP11643-Ag-1/ GM-Tg-rg-IP11643-Ag-2 Rat HNF1B protein Rat
GM-Tg-mg-IP11643-Ag-1/ GM-Tg-mg-IP11643-Ag-2 Mouse HNF1B protein Mouse
GM-Tg-cynog-IP11643-Ag-1/ GM-Tg-cynog-IP11643-Ag-2 Cynomolgus/Rhesus macaque HNF1B protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11643-Ag-1/ GM-Tg-felg-IP11643-Ag-2 Feline HNF1B protein Feline
GM-Tg-cang-IP11643-Ag-1/ GM-Tg-cang-IP11643-Ag-2 Canine HNF1B protein Canine
GM-Tg-bovg-IP11643-Ag-1/ GM-Tg-bovg-IP11643-Ag-2 Bovine HNF1B protein Bovine
GM-Tg-equg-IP11643-Ag-1/ GM-Tg-equg-IP11643-Ag-2 Equine HNF1B protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11643-Ag-1/ GM-Tg-hg-IP11643-Ag-2; GM-Tg-rg-IP11643-Ag-1/ GM-Tg-rg-IP11643-Ag-2;
GM-Tg-mg-IP11643-Ag-1/ GM-Tg-mg-IP11643-Ag-2; GM-Tg-cynog-IP11643-Ag-1/ GM-Tg-cynog-IP11643-Ag-2;
GM-Tg-felg-IP11643-Ag-1/ GM-Tg-felg-IP11643-Ag-2; GM-Tg-cang-IP11643-Ag-1/ GM-Tg-cang-IP11643-Ag-2;
GM-Tg-bovg-IP11643-Ag-1/ GM-Tg-bovg-IP11643-Ag-2; GM-Tg-equg-IP11643-Ag-1/ GM-Tg-equg-IP11643-Ag-2
Products Name HNF1B protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HNF1B
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HNF1B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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