Recombinant multi-species TCF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TCF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016]
The Alternative Names of target: 5730422P05Rik,ASP-I2,CDG2T,Class B basic helix-loop-helix protein 19 (bHLHb19),E2-2,E2.2,FCD2,FECD3,ITF-2,ITF-2b,ITF2,Immunoglobulin transcription factor 2 (ITF-2),ME2,MITF-2A,MITF-2B,PTHS,SEF-2,SEF2,SEF2-1,SEF2-1A,SEF2-1B,SEF2-1D,SL3-3 enhancer factor 2 (SEF-2),TCF-4,TCF4,TCF7L2,TFE,Tcf-4,Tcf4,Transcription factor 4,bHLHb19

Target products collectionGo to TCF4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11641-Ag-1/ GM-Tg-hg-IP11641-Ag-2 Human TCF4 protein Human
GM-Tg-rg-IP11641-Ag-1/ GM-Tg-rg-IP11641-Ag-2 Rat TCF4 protein Rat
GM-Tg-mg-IP11641-Ag-1/ GM-Tg-mg-IP11641-Ag-2 Mouse TCF4 protein Mouse
GM-Tg-cynog-IP11641-Ag-1/ GM-Tg-cynog-IP11641-Ag-2 Cynomolgus/Rhesus macaque TCF4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11641-Ag-1/ GM-Tg-felg-IP11641-Ag-2 Feline TCF4 protein Feline
GM-Tg-cang-IP11641-Ag-1/ GM-Tg-cang-IP11641-Ag-2 Canine TCF4 protein Canine
GM-Tg-bovg-IP11641-Ag-1/ GM-Tg-bovg-IP11641-Ag-2 Bovine TCF4 protein Bovine
GM-Tg-equg-IP11641-Ag-1/ GM-Tg-equg-IP11641-Ag-2 Equine TCF4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11641-Ag-1/ GM-Tg-hg-IP11641-Ag-2; GM-Tg-rg-IP11641-Ag-1/ GM-Tg-rg-IP11641-Ag-2;
GM-Tg-mg-IP11641-Ag-1/ GM-Tg-mg-IP11641-Ag-2; GM-Tg-cynog-IP11641-Ag-1/ GM-Tg-cynog-IP11641-Ag-2;
GM-Tg-felg-IP11641-Ag-1/ GM-Tg-felg-IP11641-Ag-2; GM-Tg-cang-IP11641-Ag-1/ GM-Tg-cang-IP11641-Ag-2;
GM-Tg-bovg-IP11641-Ag-1/ GM-Tg-bovg-IP11641-Ag-2; GM-Tg-equg-IP11641-Ag-1/ GM-Tg-equg-IP11641-Ag-2
Products Name TCF4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TCF4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TCF4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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