Recombinant multi-species TBX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TBX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CAFS,CATCH22,CTHM,DGCR,DGS,DORV,T-box 1,T-box protein 1,T-box transcription factor TBX1,TBX1,TBX1C,TGA,Tbx1,Testis-specific T-box protein,VCF,VCFS,nmf219

Target products collectionGo to TBX1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11625-Ag-1/ GM-Tg-hg-IP11625-Ag-2 Human TBX1 protein Human
GM-Tg-rg-IP11625-Ag-1/ GM-Tg-rg-IP11625-Ag-2 Rat TBX1 protein Rat
GM-Tg-mg-IP11625-Ag-1/ GM-Tg-mg-IP11625-Ag-2 Mouse TBX1 protein Mouse
GM-Tg-cynog-IP11625-Ag-1/ GM-Tg-cynog-IP11625-Ag-2 Cynomolgus/Rhesus macaque TBX1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11625-Ag-1/ GM-Tg-felg-IP11625-Ag-2 Feline TBX1 protein Feline
GM-Tg-cang-IP11625-Ag-1/ GM-Tg-cang-IP11625-Ag-2 Canine TBX1 protein Canine
GM-Tg-bovg-IP11625-Ag-1/ GM-Tg-bovg-IP11625-Ag-2 Bovine TBX1 protein Bovine
GM-Tg-equg-IP11625-Ag-1/ GM-Tg-equg-IP11625-Ag-2 Equine TBX1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11625-Ag-1/ GM-Tg-hg-IP11625-Ag-2; GM-Tg-rg-IP11625-Ag-1/ GM-Tg-rg-IP11625-Ag-2;
GM-Tg-mg-IP11625-Ag-1/ GM-Tg-mg-IP11625-Ag-2; GM-Tg-cynog-IP11625-Ag-1/ GM-Tg-cynog-IP11625-Ag-2;
GM-Tg-felg-IP11625-Ag-1/ GM-Tg-felg-IP11625-Ag-2; GM-Tg-cang-IP11625-Ag-1/ GM-Tg-cang-IP11625-Ag-2;
GM-Tg-bovg-IP11625-Ag-1/ GM-Tg-bovg-IP11625-Ag-2; GM-Tg-equg-IP11625-Ag-1/ GM-Tg-equg-IP11625-Ag-2
Products Name TBX1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TBX1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TBX1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.