Recombinant multi-species TRIM21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TRIM21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 52 kDa Ro protein,52 kDa ribonucleoprotein autoantigen Ro/SS-A,E3 ubiquitin-protein ligase TRIM21,RING finger protein 81,RNF81,RO52,Ro(SS-A),Ro/SSA,Ro52,SSA,SSA1,Sjoegren syndrome type A antigen (SS-A),Ssa1,TRIM21,Trim21,Tripartite motif-containing protein 21

Target products collectionGo to TRIM21 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11564-Ag-1/ GM-Tg-hg-IP11564-Ag-2 Human TRIM21 protein Human
GM-Tg-rg-IP11564-Ag-1/ GM-Tg-rg-IP11564-Ag-2 Rat TRIM21 protein Rat
GM-Tg-mg-IP11564-Ag-1/ GM-Tg-mg-IP11564-Ag-2 Mouse TRIM21 protein Mouse
GM-Tg-cynog-IP11564-Ag-1/ GM-Tg-cynog-IP11564-Ag-2 Cynomolgus/Rhesus macaque TRIM21 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11564-Ag-1/ GM-Tg-felg-IP11564-Ag-2 Feline TRIM21 protein Feline
GM-Tg-cang-IP11564-Ag-1/ GM-Tg-cang-IP11564-Ag-2 Canine TRIM21 protein Canine
GM-Tg-bovg-IP11564-Ag-1/ GM-Tg-bovg-IP11564-Ag-2 Bovine TRIM21 protein Bovine
GM-Tg-equg-IP11564-Ag-1/ GM-Tg-equg-IP11564-Ag-2 Equine TRIM21 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11564-Ag-1/ GM-Tg-hg-IP11564-Ag-2; GM-Tg-rg-IP11564-Ag-1/ GM-Tg-rg-IP11564-Ag-2;
GM-Tg-mg-IP11564-Ag-1/ GM-Tg-mg-IP11564-Ag-2; GM-Tg-cynog-IP11564-Ag-1/ GM-Tg-cynog-IP11564-Ag-2;
GM-Tg-felg-IP11564-Ag-1/ GM-Tg-felg-IP11564-Ag-2; GM-Tg-cang-IP11564-Ag-1/ GM-Tg-cang-IP11564-Ag-2;
GM-Tg-bovg-IP11564-Ag-1/ GM-Tg-bovg-IP11564-Ag-2; GM-Tg-equg-IP11564-Ag-1/ GM-Tg-equg-IP11564-Ag-2
Products Name TRIM21 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TRIM21
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TRIM21 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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