Recombinant multi-species SNRPN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SNRPN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]
The Alternative Names of target: 2410045I01Rik,HCERN3,PWCR,Peg4,RT-LI,SM-D,SMN,SNRNP-N,SNRPN,SNURF,SNURF-SNRPN,Sm protein D (Sm-D),Sm protein N (Sm-N,SmN),Small nuclear ribonucleoprotein-associated protein N,Snrpn,Tissue-specific-splicing protein,sm-D,sm-N,snRNP-N

Target products collectionGo to SNRPN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11516-Ag-1/ GM-Tg-hg-IP11516-Ag-2 Human SNRPN protein Human
GM-Tg-rg-IP11516-Ag-1/ GM-Tg-rg-IP11516-Ag-2 Rat SNRPN protein Rat
GM-Tg-mg-IP11516-Ag-1/ GM-Tg-mg-IP11516-Ag-2 Mouse SNRPN protein Mouse
GM-Tg-cynog-IP11516-Ag-1/ GM-Tg-cynog-IP11516-Ag-2 Cynomolgus/Rhesus macaque SNRPN protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11516-Ag-1/ GM-Tg-felg-IP11516-Ag-2 Feline SNRPN protein Feline
GM-Tg-cang-IP11516-Ag-1/ GM-Tg-cang-IP11516-Ag-2 Canine SNRPN protein Canine
GM-Tg-bovg-IP11516-Ag-1/ GM-Tg-bovg-IP11516-Ag-2 Bovine SNRPN protein Bovine
GM-Tg-equg-IP11516-Ag-1/ GM-Tg-equg-IP11516-Ag-2 Equine SNRPN protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11516-Ag-1/ GM-Tg-hg-IP11516-Ag-2; GM-Tg-rg-IP11516-Ag-1/ GM-Tg-rg-IP11516-Ag-2;
GM-Tg-mg-IP11516-Ag-1/ GM-Tg-mg-IP11516-Ag-2; GM-Tg-cynog-IP11516-Ag-1/ GM-Tg-cynog-IP11516-Ag-2;
GM-Tg-felg-IP11516-Ag-1/ GM-Tg-felg-IP11516-Ag-2; GM-Tg-cang-IP11516-Ag-1/ GM-Tg-cang-IP11516-Ag-2;
GM-Tg-bovg-IP11516-Ag-1/ GM-Tg-bovg-IP11516-Ag-2; GM-Tg-equg-IP11516-Ag-1/ GM-Tg-equg-IP11516-Ag-2
Products Name SNRPN protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SNRPN
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SNRPN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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