Recombinant multi-species SMARCB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMARCB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015]
The Alternative Names of target: BAF47,BRG1-associated factor 47 (BAF47),Baf47,CSS3,INI-1,INI1,Ini1,Integrase interactor 1 protein,MRD15,PPP1R144,RDT,RTPS1,SMARCB1,SNF5,SNF5 homolog (hSNF5),SNF5/INI1,SNF5L1,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1,SWNTS1,Sfh1p,Smarcb1,Snf5,Snr1,hSNFS

Target products collectionGo to SMARCB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11476-Ag-1/ GM-Tg-hg-IP11476-Ag-2 Human SMARCB1 protein Human
GM-Tg-rg-IP11476-Ag-1/ GM-Tg-rg-IP11476-Ag-2 Rat SMARCB1 protein Rat
GM-Tg-mg-IP11476-Ag-1/ GM-Tg-mg-IP11476-Ag-2 Mouse SMARCB1 protein Mouse
GM-Tg-cynog-IP11476-Ag-1/ GM-Tg-cynog-IP11476-Ag-2 Cynomolgus/Rhesus macaque SMARCB1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11476-Ag-1/ GM-Tg-felg-IP11476-Ag-2 Feline SMARCB1 protein Feline
GM-Tg-cang-IP11476-Ag-1/ GM-Tg-cang-IP11476-Ag-2 Canine SMARCB1 protein Canine
GM-Tg-bovg-IP11476-Ag-1/ GM-Tg-bovg-IP11476-Ag-2 Bovine SMARCB1 protein Bovine
GM-Tg-equg-IP11476-Ag-1/ GM-Tg-equg-IP11476-Ag-2 Equine SMARCB1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11476-Ag-1/ GM-Tg-hg-IP11476-Ag-2; GM-Tg-rg-IP11476-Ag-1/ GM-Tg-rg-IP11476-Ag-2;
GM-Tg-mg-IP11476-Ag-1/ GM-Tg-mg-IP11476-Ag-2; GM-Tg-cynog-IP11476-Ag-1/ GM-Tg-cynog-IP11476-Ag-2;
GM-Tg-felg-IP11476-Ag-1/ GM-Tg-felg-IP11476-Ag-2; GM-Tg-cang-IP11476-Ag-1/ GM-Tg-cang-IP11476-Ag-2;
GM-Tg-bovg-IP11476-Ag-1/ GM-Tg-bovg-IP11476-Ag-2; GM-Tg-equg-IP11476-Ag-1/ GM-Tg-equg-IP11476-Ag-2
Products Name SMARCB1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SMARCB1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMARCB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.