Recombinant multi-species SMARCA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMARCA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]
The Alternative Names of target: 2610209L14Rik,ATP-dependent helicase SMARCA2,BAF190,BIS,BRG1-associated factor 190B (BAF190B),BRM,NCBRS,Probable global transcription activator SNF2L2,Protein brahma homolog (hBRM),SMARCA2,SNF2,SNF2-alpha,SNF2L2,SNF2LA,SNF2alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2,SWI2,Smarca2,Snf2l2,Sth1p,brahma,brm,hBRM,hSNF2a

Target products collectionGo to SMARCA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP11473-Ag-1/ GM-Tg-hg-IP11473-Ag-2 Human SMARCA2 protein Human
GM-Tg-rg-IP11473-Ag-1/ GM-Tg-rg-IP11473-Ag-2 Rat SMARCA2 protein Rat
GM-Tg-mg-IP11473-Ag-1/ GM-Tg-mg-IP11473-Ag-2 Mouse SMARCA2 protein Mouse
GM-Tg-cynog-IP11473-Ag-1/ GM-Tg-cynog-IP11473-Ag-2 Cynomolgus/Rhesus macaque SMARCA2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP11473-Ag-1/ GM-Tg-felg-IP11473-Ag-2 Feline SMARCA2 protein Feline
GM-Tg-cang-IP11473-Ag-1/ GM-Tg-cang-IP11473-Ag-2 Canine SMARCA2 protein Canine
GM-Tg-bovg-IP11473-Ag-1/ GM-Tg-bovg-IP11473-Ag-2 Bovine SMARCA2 protein Bovine
GM-Tg-equg-IP11473-Ag-1/ GM-Tg-equg-IP11473-Ag-2 Equine SMARCA2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP11473-Ag-1/ GM-Tg-hg-IP11473-Ag-2; GM-Tg-rg-IP11473-Ag-1/ GM-Tg-rg-IP11473-Ag-2;
GM-Tg-mg-IP11473-Ag-1/ GM-Tg-mg-IP11473-Ag-2; GM-Tg-cynog-IP11473-Ag-1/ GM-Tg-cynog-IP11473-Ag-2;
GM-Tg-felg-IP11473-Ag-1/ GM-Tg-felg-IP11473-Ag-2; GM-Tg-cang-IP11473-Ag-1/ GM-Tg-cang-IP11473-Ag-2;
GM-Tg-bovg-IP11473-Ag-1/ GM-Tg-bovg-IP11473-Ag-2; GM-Tg-equg-IP11473-Ag-1/ GM-Tg-equg-IP11473-Ag-2
Products Name SMARCA2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SMARCA2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMARCA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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